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1例罕见的伴有眼眶侵犯的结膜恶性黑色素瘤。

A rare case of conjunctival malignant melanoma with orbital invasion.

作者信息

Rajbhandari Yogita, Gupta Sharad, Yadav Reena, Manandhar Ashma, Mon Aye Myat, Joshi Pramiti

出版信息

Nepal J Ophthalmol. 2019 Jan;11(21):77-81. doi: 10.3126/nepjoph.v11i1.25425.

Abstract

BACKGROUND

Conjunctival malignant melanoma is a rare ocular malignancy most commonly affecting mostly the elderly population. It is a pigmented lesion which canarise from primary acquired melanosis, de novo or from preexisting nevus.

CASE

A 63 year old male presented with a chief complaints rapidly increasing mass in the left eye for two months following trauma with a wooden stick. He had preexisting nevus in the same eye. His best corrected visual acuity was 6/12 in right eye and 1/60 left eye respectively. Slit lamp biomicroscopy examination showed 4 cm x 4 cm pigmented mass in the nasal bulbar and inferior palpebral conjunctiva causing mechanical ectropion of the lower lid with keratinization of palpebral conjunctiva. Incisionalbiopsy of conjunctiva showed malignant melanoma. On computed tomography, there was expansion of bony orbit. Considering all the findings, exenteration of the left orbitwas done. Histopathological report of exenterated mass was suggestive of malignantmelanoma of conjunctiva.

CONCLUSION

Conjunctival melanoma is a rare malignant tumor of eye which has high metastasis rate and the treatment option is surgery with adjuvant therapy.

摘要

背景

结膜恶性黑色素瘤是一种罕见的眼部恶性肿瘤,最常影响老年人群。它是一种色素性病变,可起源于原发性获得性黑色素沉着、新发或由先前存在的痣发展而来。

病例

一名63岁男性,主要主诉为左眼在被木棍打伤两个月后肿物迅速增大。他同一只眼睛先前有痣。他的最佳矫正视力右眼为6/12,左眼为1/60。裂隙灯显微镜检查显示鼻侧球结膜和下睑结膜有一个4厘米×4厘米的色素性肿物,导致下睑机械性外翻,睑结膜角化。结膜切开活检显示为恶性黑色素瘤。计算机断层扫描显示眼眶骨质扩大。综合所有检查结果,对左眼进行了眼眶内容物剜除术。剜除肿物的组织病理学报告提示为结膜恶性黑色素瘤。

结论

结膜黑色素瘤是一种罕见的眼部恶性肿瘤,转移率高,治疗选择是手术加辅助治疗。

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