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类风湿性神经病变:简要概述

Rheumatoid Neuropathy: A Brief Overview.

作者信息

Rajeshwari Bhavya, Kumar Sunil

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2023 Jan 24;15(1):e34127. doi: 10.7759/cureus.34127. eCollection 2023 Jan.

Abstract

Rheumatoid arthritis is an autoimmune disease commonly found in humans. It is characterized by stiffness and swelling of the joints, along with fatigue and malaise. Rheumatoid neuropathy is a neuropathy that arises as a complication of rheumatoid arthritis. The primary objective of this review article is to provide a detailed account of the various aspects of this neurological complication ranging from its incidence, clinical features, and diagnosis. After searching through various published review articles and textbooks, rheumatoid neuropathy is one of the most common complications of rheumatoid arthritis. Out of all types of neuropathies. the most observed is entrapment neuropathy. Carpel tunnel syndrome is the most common type of entrapment neuropathy. There seems to be a greater predilection of rheumatoid neuropathy in females compared to males. A direct relation exists between rheumatoid factor and the occurrence of neuropathy. Some clinical features of rheumatoid neuropathy include stiffness in hands and feet, burning and tingling, stabbing pain, occasional weakness, and numbness in several cases. The common modalities of diagnosis are history, clinical examination, blood test, magnetic resonance imaging, nerve conduction study, and tissue biopsy. From the above-mentioned modalities, nerve conduction studies must be chosen as they can detect latent cases quickly and effective treatment can be initiated immediately. Finally, we outline the treatment plan for the disease which can be divided into medical and surgical management. Medical management consists of symptomatic treatment such as analgesics, anticonvulsants, and antidepressants, while surgical management is the last resort and consists of nerve compression.

摘要

类风湿性关节炎是一种常见于人类的自身免疫性疾病。其特征为关节僵硬、肿胀,伴有疲劳和不适。类风湿性神经病变是类风湿性关节炎引发的一种神经病变。这篇综述文章的主要目的是详细阐述这种神经并发症的各个方面,包括其发病率、临床特征和诊断。在查阅了各种已发表的综述文章和教科书后发现,类风湿性神经病变是类风湿性关节炎最常见的并发症之一。在所有类型的神经病变中,最常观察到的是卡压性神经病变。腕管综合征是最常见的卡压性神经病变类型。与男性相比,女性似乎更容易患类风湿性神经病变。类风湿因子与神经病变的发生之间存在直接关系。类风湿性神经病变的一些临床特征包括手脚僵硬、灼痛和刺痛感、刺痛、偶尔出现的无力,以及在某些情况下的麻木。常见的诊断方式有病史、临床检查、血液检查、磁共振成像、神经传导研究和组织活检。从上述方式中,必须选择神经传导研究,因为它们可以快速检测出潜在病例,并能立即开始有效治疗。最后,我们概述了该疾病的治疗方案,可分为药物治疗和手术治疗。药物治疗包括对症治疗,如使用镇痛药、抗惊厥药和抗抑郁药,而手术治疗是最后的手段,包括神经减压术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7854/9947570/6da21e1b3e1e/cureus-0015-00000034127-i01.jpg

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