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类风湿关节炎治疗的当前治疗选择

Current Therapeutic Options in the Treatment of Rheumatoid Arthritis.

作者信息

Köhler Birgit M, Günther Janine, Kaudewitz Dorothee, Lorenz Hanns-Martin

机构信息

Internal Medicine 5, Division of Rheumatology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

出版信息

J Clin Med. 2019 Jun 28;8(7):938. doi: 10.3390/jcm8070938.

Abstract

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints. Untreated RA leads to a destruction of joints through the erosion of cartilage and bone. The loss of physical function is the consequence. Early treatment is important to control disease activity and to prevent joint destruction. Nowadays, different classes of drugs with different modes of action are available to control the inflammation and to achieve remission. In this review, we want to discuss differences and similarities of these different drugs.

摘要

类风湿性关节炎(RA)是一种全身性自身免疫性疾病,其特征为关节的慢性炎症。未经治疗的类风湿性关节炎会通过软骨和骨骼的侵蚀导致关节破坏。身体功能丧失就是其后果。早期治疗对于控制疾病活动和预防关节破坏很重要。如今,有不同作用方式的各类药物可用于控制炎症并实现病情缓解。在本综述中,我们想要探讨这些不同药物的异同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33a/6678427/0931b355f6c2/jcm-08-00938-g001.jpg

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