With the launch of the Prisms Global Mental Health series, we are taking the opportunity to make explicit our vision for Global Mental Health. We strongly propose a Public Mental Health approach, incorporating culture and context and prioritizing equity and inclusion, particularly of previously marginalized groups. In using a Public Mental Health approach, we are framing Global Mental Health research as population-oriented research that seeks to understand the etiology, prevention, promotion, and treatment of mental and behavioral health problems with a strong emphasis on 'knowledge generation' which is relevant, transferable, and generalizable to different populations and settings. The public health approach also incorporates policy and systems research and evaluation, with a particular focus on accessibility and quality of care and human rights. By using the term Global, we are being explicit in acknowledging the role(s) of culture and context in all stages of research, from conceptualization through interpretation and dissemination. In centering equity and inclusion, we are advocating for a focus on populations who have been marginalized and have not been well represented within Global Mental Health research and active participation of voices of the populations that are included in the research. We are also working to promote participation of individuals from diverse and underrepresented communities and diverse experiences, including those with lived experience, in all stages of research pipeline: from conceptualization to publication of findings. Our readers will see these values and ideas operationalized in the choice of article topics and the published manuscripts as well as in the editorial and advisory board membership and selection of reviewers.