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Anticoagulation for cardiopulmonary bypass: part one.体外循环抗凝：第一部分。
BJA Educ. 2023 Mar;23(3):110-116. doi: 10.1016/j.bjae.2022.12.003. Epub 2023 Jan 23.
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Effect of anticoagulation protocol on outcome in patients undergoing CABG with heparin-bonded cardiopulmonary bypass circuits.抗凝方案对使用肝素涂层体外循环回路行冠状动脉旁路移植术患者结局的影响。
Ann Thorac Surg. 1998 Feb;65(2):425-33. doi: 10.1016/s0003-4975(97)01347-7.
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Anticoagulation for cardiopulmonary bypass, Part 2: alternatives and pathological states.体外循环抗凝，第2部分：替代方法与病理状态
BJA Educ. 2023 Jul;23(7):256-263. doi: 10.1016/j.bjae.2023.03.008. Epub 2023 Jun 7.
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Volatile anaesthesia during cardiopulmonary bypass.体外循环期间的挥发性麻醉
Perfusion. 2015 Jan;30(1):6-16. doi: 10.1177/0267659114531314. Epub 2014 Apr 14.
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Selective anticoagulation with active site-blocked factor IXA suggests separate roles for intrinsic and extrinsic coagulation pathways in cardiopulmonary bypass.活性位点被阻断的IX因子选择性抗凝表明内源性和外源性凝血途径在体外循环中发挥不同作用。
J Thorac Cardiovasc Surg. 1998 Nov;116(5):860-9. doi: 10.1016/S0022-5223(98)00437-1.
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Heparin resistance after intraoperative platelet-rich plasma harvesting.术中采集富血小板血浆后出现肝素抵抗。
J Thorac Cardiovasc Surg. 1992 Jun;103(6):1172-6.
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Massive atrial myxoma requiring emergency cardiopulmonary bypass in a patient with heparin resistance.一名肝素抵抗患者患有巨大心房黏液瘤，需要进行紧急体外循环。
Anaesth Rep. 2020 Aug 9;8(2):103-106. doi: 10.1002/anr3.12063. eCollection 2020 Jul-Dec.
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Anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II and renal impairment using heparin and the platelet glycoprotein IIb-IIIa antagonist tirofiban.在患有Ⅱ型肝素诱导的血小板减少症和肾功能损害的患者进行体外循环期间，使用肝素和血小板糖蛋白IIb-IIIa拮抗剂替罗非班进行抗凝。
Anesthesiology. 2001 Feb;94(2):245-51. doi: 10.1097/00000542-200102000-00013.
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A change in anticoagulation monitoring improves safety, reduces transfusion, and reduces costs in infants on cardiopulmonary bypass.抗凝监测的改变可提高体外循环下婴儿的安全性、减少输血并降低成本。
Paediatr Anaesth. 2015 Jun;25(6):580-6. doi: 10.1111/pan.12591. Epub 2014 Dec 21.
引用本文的文献
1
Anticoagulation for cardiopulmonary bypass, Part 2: alternatives and pathological states.体外循环抗凝，第2部分：替代方法与病理状态
BJA Educ. 2023 Jul;23(7):256-263. doi: 10.1016/j.bjae.2023.03.008. Epub 2023 Jun 7.
本文引用的文献
1
Heparin Resistance - Clinical Perspectives and Management Strategies.肝素抵抗——临床观点与管理策略
N Engl J Med. 2021 Aug 26;385(9):826-832. doi: 10.1056/NEJMra2104091.
2
Optimal protamine dosing after cardiopulmonary bypass: The PRODOSE adaptive randomised controlled trial.心脏体外循环后鱼精蛋白最佳剂量：PRODOSE 适应性随机对照试验。
PLoS Med. 2021 Jun 7;18(6):e1003658. doi: 10.1371/journal.pmed.1003658. eCollection 2021 Jun.
3
Is There a "Blind Spot" in Point-of-Care Testing for Residual Heparin After Cardiopulmonary Bypass? A Prospective, Observational Cohort Study.体外循环后残余肝素的即时检验是否存在“盲区”？一项前瞻性观察队列研究。
Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029620946843. doi: 10.1177/1076029620946843.
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Toward Optimal Anticoagulation Monitoring During Cardiopulmonary Bypass: It Is Still A Tough "ACT".体外循环期间实现最佳抗凝监测：这仍是一项艰巨的“活化凝血时间（ACT）”任务。
J Cardiothorac Vasc Anesth. 2020 Nov;34(11):2928-2930. doi: 10.1053/j.jvca.2020.07.024. Epub 2020 Jul 10.
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A 0.6-protamine/heparin ratio in cardiac surgery is associated with decreased transfusion of blood products.心脏手术中 0.6 的鱼精蛋白/肝素比率与减少血液制品的输注有关。
Interact Cardiovasc Thorac Surg. 2020 Sep 1;31(3):391-397. doi: 10.1093/icvts/ivaa109.
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Evaluation of Point-of-Care ACT Coagulometers and Anti-Xa Activity During Cardiopulmonary Bypass.体外循环期间即时 ACT 凝血仪和抗 Xa 活性的评估。
J Cardiothorac Vasc Anesth. 2020 Nov;34(11):2921-2927. doi: 10.1053/j.jvca.2020.06.027. Epub 2020 Jun 12.
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Heparin Dose and Point-of-Care Measurements of Hemostasis in Cardiac Surgery-Results of a Randomized Controlled Trial.肝素剂量和心脏手术中止血的即时检测——一项随机对照试验的结果。
J Cardiothorac Vasc Anesth. 2020 Sep;34(9):2362-2368. doi: 10.1053/j.jvca.2019.12.050. Epub 2020 Jan 7.
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2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery.2019年欧洲心胸外科学会/欧洲心胸麻醉学会/欧洲体外循环学会成人心脏手术体外循环指南。
Eur J Cardiothorac Surg. 2020 Feb 1;57(2):210-251. doi: 10.1093/ejcts/ezz267.
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Anticoagulant and side-effects of protamine in cardiac surgery: a narrative review.心脏手术中抗凝剂与鱼精蛋白的副作用：一篇叙述性综述。
Br J Anaesth. 2018 May;120(5):914-927. doi: 10.1016/j.bja.2018.01.023. Epub 2018 Feb 26.
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The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: Clinical Practice Guidelines-Anticoagulation During Cardiopulmonary Bypass.美国胸外科医师学会、心血管麻醉医师学会和美国体外循环技术学会：体外循环期间抗凝的临床实践指南。
Ann Thorac Surg. 2018 Feb;105(2):650-662. doi: 10.1016/j.athoracsur.2017.09.061. Epub 2018 Jan 19.
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