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阴茎假体手术时的空腹血糖与糖化血红蛋白水平及手术结果的相关性。

Correlation of fasting blood sugar at the time of penile prosthesis surgery with the level of glycated hemoglobin and the outcome of surgery.

作者信息

Haobus Mohamad, Almannie Raed, Aziz Mohammed, Farag Mohammed, Ralph David, Mulhall John, Binsaleh Saleh

机构信息

Urology, Al-Themal Medical Center, Abha, Saudi Arabia.

Division of Urology, Department of Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Afr J Urol. 2021;27. doi: 10.1186/s12301-021-00198-y. Epub 2021 Jul 2.

DOI:10.1186/s12301-021-00198-y
PMID:36844698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9957561/
Abstract

BACKGROUND

The role of glycemic control in predicting implant infection and other surgical complications is debatable. This study aimed to assess the potential correlation between fasting blood sugar (FBS) levels prior to penile prosthesis surgery (PPS) and the surgical outcomes.

METHODS

A retrospective study from data collected prospectively in 2015 in a single center. Patients who underwent penile implant procedures were included. Exclusion criteria were if surgery done by low-volume implanter, patients who required revision surgery or not diagnosed with diabetes mellitus. Management was standardized to all patients.

RESULTS

All complications whether minor or major were documented up to three years. One year after the surgery a Likert scale questionnaire was completed by the patients. In total, 218 patients completed the study at last follow-up. Complications rate was 6.25%. The rate of infection requiring explantation was 3.8%. 0.9% of patients had a superficial infection managed successfully with conservative management. 0.9% had erosion and 0.9% had mechanical failure. There was no statistically significant difference in FBS or glycated hemoglobin (HbA1c) levels in patients with postoperative complications compared to patients with satisfactory postoperative course. FBS level on the day of surgery was within 20 mg/dL (1.11 mmol/L) of the expected range based on HbA1c measurement in 62 patients (28.44%), while in 146 patients (66.98%) the FBS was not within 20 mg/dl (1.11 mmol/L) of the expected range based on preoperative HbA1c level.

CONCLUSION

FBS levels on the day of surgery are not correlated with HbA1c levels and PPS outcomes.

摘要

背景

血糖控制在预测植入物感染及其他手术并发症方面的作用存在争议。本研究旨在评估阴茎假体手术(PPS)前空腹血糖(FBS)水平与手术结果之间的潜在相关性。

方法

一项回顾性研究,数据来自2015年在单一中心前瞻性收集的资料。纳入接受阴茎植入手术的患者。排除标准为手术由低容量植入者进行、需要翻修手术或未诊断为糖尿病的患者。对所有患者的管理进行标准化。

结果

记录了所有并发症,无论轻微还是严重,随访期长达三年。术后一年患者完成了李克特量表问卷调查。最终随访时共有218例患者完成研究。并发症发生率为6.25%。需要取出植入物的感染率为3.8%。0.9%的患者发生浅表感染,经保守治疗成功治愈。0.9%的患者发生侵蚀,0.9%的患者发生机械故障。与术后病程满意的患者相比,术后出现并发症的患者FBS或糖化血红蛋白(HbA1c)水平无统计学显著差异。62例患者(28.44%)手术当天的FBS水平在基于HbA1c测量预期范围的20 mg/dL(1.11 mmol/L)之内,而146例患者(66.98%)的FBS不在基于术前HbA1c水平预期范围的20 mg/dl(1.11 mmol/L)之内。

结论

手术当天的FBS水平与HbA1c水平及PPS结果无关。