Yanar Fatih, Öner Gizem, Yüksel Sercan, Salduz Ahmet, Azamat İbrahim Fethi, Özçınar Beyza, Bilgic Bilge, Günöz Cömert Rana, Kozanoğlu Erol, Kurtoğlu Mehmet
Department of General Surgery, İstanbul University Faculty of Medicine, İstanbul, Türkiye.
Multidisciplinary Oncologic Centre (MOCA), Antwerpen University Hospital, Antwerpen, Belgium.
Turk J Surg. 2022 Sep 19;38(3):306-311. doi: 10.47717/turkjsurg.2022.4381. eCollection 2022 Sep.
Intimal angiosarcoma is a rare vascular malignancy, and diagnosis is very difficult due to nonspecific symptoms. There are controversial points regarding the diagnosis, treatment and follow-up of intimal angiosarcomas. The purpose of this case report was to evaluate the diagnosis and treatment process of a patient diagnosed with femoral artery intimal angiosarcoma. Furthermore, in line with previous studies, it was aimed to illuminate controversial points. A 33-year-old male patient, who had been operated on due to ruptured femoral artery aneurysm, was diagnosed with intimal angiosarcoma with the pathology result. Recurrence was observed during clinical follow-up, and the patient was treated with chemotherapy and radiotherapy. Since there was no response to treatment, the patient underwent aggressive surgery including the surrounding tissues. No recurrence or metastasis was observed in the patient's 10 month follow-up. Although intimal angiosarcoma is rare, it should be considered in differential diagnosis when femoral artery aneurysm is detected. The most important step in treatment is aggressive surgery, but adding chemo-radiotherapy to the treatment should be considered.
内膜血管肉瘤是一种罕见的血管恶性肿瘤,由于症状不具特异性,诊断非常困难。关于内膜血管肉瘤的诊断、治疗及随访存在一些争议点。本病例报告的目的是评估一名被诊断为股动脉内膜血管肉瘤患者的诊断和治疗过程。此外,与先前的研究一致,旨在阐明争议点。一名33岁男性患者因股动脉动脉瘤破裂接受手术,病理结果诊断为内膜血管肉瘤。临床随访期间观察到复发,该患者接受了化疗和放疗。由于对治疗无反应,患者接受了包括周围组织在内的根治性手术。在患者10个月的随访中未观察到复发或转移。尽管内膜血管肉瘤罕见,但在检测到股动脉动脉瘤时,应在鉴别诊断中予以考虑。治疗中最重要的步骤是根治性手术,但应考虑在治疗中加入放化疗。