Suppr超能文献

在人工耳蜗植入效果有限的人群中,合并症与更差的预后相关。

Comorbidity associated with worse outcomes in a population of limited cochlear implant performers.

作者信息

Lee Erika, Pisa Justyn, Hochman Jordan

机构信息

University of Manitoba Faculty of Medicine Otolaryngology - Head and Neck Surgery Winnipeg Manitoba Canada.

University of Manitoba Faculty of Medicine Surgical Hearing Implant Program, Department of Otolaryngology-Head and Neck Surgery Winnipeg Manitoba Canada.

出版信息

Laryngoscope Investig Otolaryngol. 2022 Dec 16;8(1):230-235. doi: 10.1002/lio2.985. eCollection 2023 Feb.

Abstract

INTRODUCTION

Most patients significantly benefit from cochlear implantation (CI). However, speech understanding varies widely, with a small proportion of patients demonstrating limited audiometric outcomes. While there are well-documented determinants of poor performance, there remains a cohort of patients that do not meet expected outcomes. Preoperative prognostication is desirable to manage expectations, ensure value of the intervention, and reduce risk. The objective of the study is to evaluate variables found within a single CI center's most limited functioning cohort following implantation.

METHODS

A retrospective review of a single CI program's cohort of (344 ears) patients implanted between 2011 and 2018 whose 1-year postimplantation AzBio scores fall 2 SDs below the mean was performed. Exclusion criteria includes skullbase pathology, pre/peri-lingual deafness, cochlear anatomic abnormalities, English as an additional language, and limited electrode insertion depth. Overall, 26 patients were identified.

RESULTS

The study population's postimplantation net benefit AzBio score is 18% compared to the entire program's 47% ( < 0.05). This group is older (71.8 vs. 59.0 years,  < 0.05) with a longer duration of hearing loss (26.4 vs. 18.0 years,  < 0.05) and with a lower preoperative AzBio score [14% lower ( < 0.05)]. A host of medical conditions were identified in the subpopulation, with a trend towards significance in those suffering from either malignancy or cardiac condition. Escalating comorbid status was associated with worse performance ( < 0.05).

CONCLUSION

Within a cohort of limited-performing CI users, benefit tended to decrease with escalating number of comorbid conditions. This information may serve to inform preoperative patient counseling.

LEVEL OF EVIDENCE

Level IV (evidence from a case control study).

摘要

引言

大多数患者从人工耳蜗植入(CI)中显著获益。然而,言语理解能力差异很大,一小部分患者的听力测量结果有限。虽然有充分记录的导致表现不佳的决定因素,但仍有一批患者未达到预期结果。术前进行预后评估有助于管理预期、确保干预的价值并降低风险。本研究的目的是评估在单个CI中心植入后功能最受限的队列中发现的变量。

方法

对2011年至2018年间植入人工耳蜗的(344耳)患者队列进行回顾性研究,这些患者植入后1年的AzBio评分比平均值低2个标准差。排除标准包括颅底病变、语前/语期耳聋、耳蜗解剖异常、英语为附加语言以及电极插入深度受限。总体而言,共确定了26例患者。

结果

与整个项目的47%相比,研究人群植入后的净获益AzBio评分为18%(P<0.05)。该组患者年龄较大(71.8岁对59.0岁,P<0.05),听力损失持续时间较长(26.4年对18.0年,P<0.05),术前AzBio评分较低[低14%(P<0.05)]。在亚组中发现了一系列医疗状况,患有恶性肿瘤或心脏病的患者有显著趋势。共病状态的增加与表现较差相关(P<0.05)。

结论

在人工耳蜗植入效果有限用户队列中,随着共病状况数量的增加,获益往往会减少。这些信息可能有助于术前对患者进行咨询。

证据水平

IV级(病例对照研究证据)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6e4/9948576/f0026d7aece4/LIO2-8-230-g003.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验