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用于大规模伤亡事件应急准备的神经毒剂解毒剂剂量工具的使用。

Use of a Nerve Agent Antidote-Dosing Tool for Mass Casualty Incident Emergency Preparedness.

机构信息

NYU Langone Hospital - Brooklyn, Department of Pharmacy, Brooklyn, New York, USA.

NYU Langone Hospital - Brooklyn, Department of Emergency Medicine, Brooklyn, New York, USA.

出版信息

Disaster Med Public Health Prep. 2023 Feb 27;17:e337. doi: 10.1017/dmp.2023.5.

DOI:10.1017/dmp.2023.5
PMID:36847261
Abstract

OBJECTIVE

Nerve agent attacks pose a serious threat worldwide and ensuring optimal readiness is essential to management. We review a mass casualty incident (MCI) drill in a busy urban New York City Emergency Department incorporating an antidote-dosing tool.

METHODS

Emergency Management and Preparedness planned an MCI drill involving a nerve agent exposure and engaged the pharmacy department to participate on a more comprehensive level. The clinical pharmacist prepared a treatment tool with antidote dosing recommendations to distribute to team members participating in the drill.

RESULTS

During the launch of the exercise, all clinicians involved reviewed the antidote-dosing tool with the pharmacy team members. Because of the ease of use, limited time was necessary to review the dosing tool before the start of the exercise. After the exercise, feedback regarding the use of the tool was very positive and participants appreciated the tool for use in a theoretical emergency that they have had limited experience managing.

CONCLUSIONS

Optimizing team preparedness with accessible and practical dosing tools may be a helpful addition to emergency preparedness for chemical and biological events with the potential for many casualties.

摘要

目的

神经毒剂袭击在全球范围内构成严重威胁,确保做好最佳准备对于此类事件的管理至关重要。我们回顾了在纽约市一家繁忙的市区急诊部进行的涉及解毒剂剂量工具的大规模伤亡事件演习。

方法

应急管理和准备部门计划进行一次涉及神经毒剂暴露的大规模伤亡事件演习,并让药剂科部门更全面地参与进来。临床药剂师准备了一个治疗工具,其中包含解毒剂剂量建议,分发给参与演习的团队成员。

结果

在演习启动时,所有参与的临床医生都与药剂科团队成员一起审查了解毒剂剂量工具。由于该工具易于使用,因此在演习开始前,只需很少的时间来复习剂量工具。演习结束后,对该工具使用情况的反馈非常积极,参与者赞赏该工具可用于他们处理经验有限的理论紧急情况。

结论

优化团队的准备工作,提供易于获取且实用的剂量工具,可能有助于为可能导致大量伤亡的化学和生物事件的应急准备工作提供帮助。

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引用本文的文献

1
Impact of antidote quantity, timing and prehospital strategies in nerve agent mass casualty events: a simulation study.解毒剂用量、给药时机及院前策略在神经毒剂大规模伤亡事件中的影响:一项模拟研究
Front Public Health. 2025 Aug 26;13:1640554. doi: 10.3389/fpubh.2025.1640554. eCollection 2025.