两名在产前诊断为20号染色体三体嵌合体后出生的六岁男孩发育正常。
Normal development in two six-year-old boys born after prenatal diagnosis of trisomy 20 mosaicism.
作者信息
Tolmie J L, Ferguson-Smith M E, Gilmore D, Ferguson-Smith M A
机构信息
Duncan Guthrie Institute of Medical Genetics, Yorkhill Hospitals, Glasgow, U.K.
出版信息
Prenat Diagn. 1987 Oct;7(8):597-601. doi: 10.1002/pd.1970070810.
PMID:3684964
Abstract
Prenatal diagnosis of trisomy 20 mosaicism was made in two pregnancies by chromosome analysis of cultured amniotic fluid cells. In both cases, the pregnancy continued to term and a healthy male infant was delivered. Regular assessments up to the age of 6.5 years revealed normal physical and intellectual development in both children.
摘要
通过对培养的羊水细胞进行染色体分析，在两例妊娠中做出了20三体嵌合体的产前诊断。在这两例中，妊娠均持续至足月，并分娩出健康男婴。对两名儿童直至6.5岁的定期评估显示，两人身体和智力发育均正常。
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