Di Duca Fabiana, Montuori Paolo, Trama Ugo, Masucci Armando, Borrelli Gennaro Maria, Triassi Maria
Department of Public Health, University "Federico II", Via Sergio Pansini n° 5, 80131 Naples, Italy.
General Directorate of Health, Campania Region, Centro Direzionale Is. C3, 80143 Naples, Italy.
Toxics. 2023 Feb 13;11(2):172. doi: 10.3390/toxics11020172.
Increased concerns about the toxicities of Polycyclic Aromatic Hydrocarbons (PAHs), ubiquitous and persistent compounds, as well as the associated ecotoxicology issue in estuarine sediments, have drawn attention worldwide in the last few years. The levels of PAHs in the Sele, Sarno, and Volturno Rivers sediments were evaluated. Moreover, the cancerogenic risk resulting from dermal and ingestion exposure to PAHs was estimated using the incremental lifetime cancer risk (ILCR) assessment and the toxic equivalent concentration (TEQ). For Sele River, the results showed that the total PAH concentration ranged from 632.42 to 844.93 ng g dw, with an average value of 738.68 ng g dw. ∑PAHs were in the range of 5.2-678.6 ng g dw and 434.8-872.1 ng g dw for the Sarno and Volturno River sediments, respectively. The cancerogenic risk from the accidental ingestion of PAHs in estuarine sediments was low at all sampling sites. However, based on the ILCR values obtained, the risk of cancer associated with exposure by dermal contact with the PAHs present in the sediments was moderate, with a mean ILCR value of 2.77 × 10. This study revealed the pollution levels of PAHs across the South of Italy and provided a scientific basis for PAH pollution control and environmental protection.
近年来，多环芳烃（PAHs）作为普遍存在且持久的化合物，其毒性以及河口沉积物中相关的生态毒理学问题日益受到全球关注。对塞莱河、萨诺河和沃尔图诺河沉积物中的多环芳烃水平进行了评估。此外，使用终生癌症风险增量（ILCR）评估和毒性当量浓度（TEQ）估算了皮肤接触和摄入多环芳烃所导致的致癌风险。对于塞莱河，结果表明总多环芳烃浓度范围为632.42至844.93 ng/g干重，平均值为738.68 ng/g干重。萨诺河和沃尔图诺河沉积物中∑PAHs的范围分别为5.2 - 678.6 ng/g干重和434.8 - 872.1 ng/g干重。在所有采样点，河口沉积物中多环芳烃意外摄入的致癌风险较低。然而，根据获得的ILCR值，与皮肤接触沉积物中多环芳烃相关的癌症风险为中度，平均ILCR值为2.77×10。本研究揭示了意大利南部多环芳烃的污染水平，为多环芳烃污染控制和环境保护提供了科学依据。
