Eppe Justine, Djebala Salem, Rollin Frédéric, Guyot Hugues
Clinical Department of Production Animals, Fundamental and Applied Research for Animals & Health Research Unit (FARAH), Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 7A-7D, 4000 Liège, Belgium.
Murphy and Leslie Veterinary Center (Private Practice), Muckerstaff Granard, N39AN52 Co Longford, Ireland.
Vet Sci. 2023 Feb 12;10(2):149. doi: 10.3390/vetsci10020149.
In ruminants, the main documented clinical manifestation of aluminium (Al) intoxication is similar to grass tetany. In a 50 dairy cow Belgian herd, the farmer reported excessive uterine bleeding at calving and decreased milk production. Dairy cows received a mixed ration (MR) with high Al concentration (453 ppm/kg of dry matter (DM)). Various analyses were sampled from 10 sick cows and compared with 10 healthy cows (from another herd). Sick cows presented anaemia and marginal hypozincaemia and 6/10 showed subclinical ketosis. Their urine analysis revealed hypomagnesaemia and a high Al/creatinine ratio. It was advised to determine soil pH, add salts to the ration to chelate the Al and support cows with mineral supplements and propylene glycol. A visit was carried out 2 years later and highlighted an improvement in the situation, but all examined animals presented subclinical ketosis. Grass silage Al content remained high (700 ppm/kg DM), as did butyric acid concentration (11.22 g/kg DM). Al could be incriminated at different stages: micronutrient deficiencies, anaemia and negative energy balance. However, Al was probably not the only culprit. This case report is a concern for future years in these areas due to droughts, scarcity of forage and an increase in contaminated soil ingestion.
在反刍动物中,铝(Al)中毒的主要临床表现与青草搐搦相似。在比利时的一个50头奶牛群中,养殖户报告称奶牛产犊时子宫出血过多且产奶量下降。奶牛食用了铝浓度较高(453 ppm/kg干物质(DM))的混合日粮(MR)。从10头病牛身上采集了各种分析样本,并与10头健康奶牛(来自另一个牛群)进行比较。病牛出现贫血和边缘性低锌血症,10头中有6头表现出亚临床酮病。它们的尿液分析显示低镁血症和高铝/肌酐比值。建议测定土壤pH值,在日粮中添加盐以螯合铝,并为奶牛补充矿物质和丙二醇。两年后进行了一次走访,情况有所改善,但所有检查的动物都存在亚临床酮病。青贮草中的铝含量仍然很高(700 ppm/kg DM),丁酸浓度也是如此(11.22 g/kg DM)。铝可能在不同阶段起作用:微量营养素缺乏、贫血和负能量平衡。然而,铝可能不是唯一的罪魁祸首。由于干旱、草料短缺以及受污染土壤摄入量增加,该病例报告对这些地区未来几年来说是一个令人担忧的问题。