晨礼对老年女性氧化应激的影响：一项随机对照试验。
Salat dhuha effect on oxidative stress in elderly women: A randomized controlled trial.
作者信息
Boy Elman, Lelo Aznan
机构信息
Department of Public Health, Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara, Medan, Indonesia.
Department of Medicine and Therapeutics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
出版信息
Saudi J Biol Sci. 2023 Apr;30(4):103603. doi: 10.1016/j.sjbs.2023.103603. Epub 2023 Feb 23.
BACKGROUND
The aging process and a chronic sedentary lifestyle in the elderly as a result of physical restrictions during the COVID-19 pandemic, induces oxidative stress through oxygen supply and antioxidant activity imbalance which in turn induce degenerative diseases. Salat dhuha as a prayer and mind-body medicine which is practiced by the Muslim community can hopefully be a solution to decrease oxidative stress in the elderly.
OBJECTIVE
To evaluate the acute physiological effects of salat dhuha on Glutathione Peroxidase activity (GPx) as an antioxidant and Malondialdehyde (MDA) as an oxidant in healthy elderly Muslim women population who have done salat dhuha regularly.
METHOD
A randomized controlled study was done on elderly women (aged 60-74 years old) who are treated in the North Sumatra Government's Nursing Home in Binjai and who routinely do 2 rakaat of salat dhuha every day. Several physical, clinical, and blood examinations were done pre and post-intervention. 101 elderly Muslim women in the nursing home were selected, 26 met the study criteria and were included in the study. The volunteers were randomized into 2 groups using lottery papers, the "2-rakaat salat dhuha group" (n = 13) and the "8-rakaat salat dhuha group" (n = 13). All volunteers did salat dhuha for at least 5 days per week for 6 weeks.
RESULT
24 elderly women completed the study, and one volunteer from each group dropped out. The characteristics of participants from both groups were homogenous. Results of the -independent analysis showed that MDA concentrations in both groups in the pre and post-test were not significantly different (p > 0,05). Mann Whitney analysis showed that GPx on both groups in the pre and post-test were not significantly different (p > 0,05). Paired sample -test analysis on the MDA concentrations pre and post-test in the 8-rakaat group showed a significant difference in MDA levels (p < 0,05). The 8-rakaat salat dhuha group showed that GPx activity increases as much as 8,9% and MDA levels decrease as much as 48,35 % after 6 weeks.
CONCLUSION
Salat dhuha promotes redox homeostasis and has the potential to prevent oxidative stress in elderly women.
背景
由于新冠疫情期间身体活动受限，老年人的衰老过程和长期久坐的生活方式会通过氧气供应和抗氧化活性失衡引发氧化应激，进而诱发退行性疾病。晌礼作为穆斯林群体践行的一种祈祷和身心疗法，有望成为减轻老年人氧化应激的一种解决方案。
目的
评估晌礼对定期进行晌礼的健康老年穆斯林女性群体中作为抗氧化剂的谷胱甘肽过氧化物酶活性（GPx）和作为氧化剂的丙二醛（MDA）的急性生理影响。
方法
对在棉兰勿老湾的北苏门答腊省政府养老院接受治疗且每天常规进行两拜晌礼的老年女性（年龄60 - 74岁）进行了一项随机对照研究。在干预前后进行了多项身体检查和血液检查。从养老院的101名老年穆斯林女性中选取，26名符合研究标准并纳入研究。志愿者通过抽签随机分为两组，即“两拜晌礼组”（n = 13）和“八拜晌礼组”（n = 13）。所有志愿者每周至少进行5天晌礼，持续6周。
结果
24名老年女性完成了研究，每组各有一名志愿者退出。两组参与者的特征相似。独立分析结果显示，两组在测试前后的MDA浓度无显著差异（p > 0.05）。曼-惠特尼分析表明，两组在测试前后的GPx无显著差异（p > 0.05）。对八拜晌礼组测试前后的MDA浓度进行配对样本检验分析显示，MDA水平有显著差异（p < 0.05）。八拜晌礼组显示，6周后GPx活性增加了8.9%，MDA水平降低了48.35%。
结论
晌礼可促进氧化还原稳态，具有预防老年女性氧化应激的潜力。
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