Channer K S, James M A, Papouchado M, Rees J R
Department of Cardiology, Bristol Royal Infirmary.
Q J Med. 1987 Apr;63(240):315-22.
Seventy-two patients with chest pain and negative exercise tests were observed. Twenty-one (29 per cent) became pain free but 51 (71 per cent) continued to complain of chest pain. Patients with persistent pain were significantly more anxious and depressed at presentation and later compared with those who had become pain free. Anxiety and particularly depression, at presentation and later, were significantly associated with severe symptoms. Patients with chest pain associated with neurosis and depression are not reassured by physiological stress testing because their physical symptoms are a feature of underlying psychiatric disease.
观察了72例胸痛且运动试验阴性的患者。21例（29%）胸痛消失，但51例（71%）仍持续诉说胸痛。与胸痛消失的患者相比，持续疼痛的患者在就诊时及之后明显更焦虑和抑郁。就诊时及之后的焦虑，尤其是抑郁，与严重症状显著相关。伴有神经症和抑郁的胸痛患者不会因生理应激试验而安心，因为他们的躯体症状是潜在精神疾病的一个特征。
