Benacerraf B R, Pober B R, Sanders S P
Department of Radiology, Harvard Medical School, Boston, MA.
Radiology. 1987 Dec;165(3):847-9. doi: 10.1148/radiology.165.3.3685364.
The reliability of prenatal ultrasound (US) for the detection of structural heart defects was investigated in a consecutive population of patients referred for prenatal US. Twenty-eight of 49 fetuses (57%) shown to have one or more heart defects with physical examination or autopsy were found to have congenital heart disease with prenatal US. There were 66 cardiac defects in 49 fetuses, 33 of which were entirely or partly identified (50%). Defects correctly diagnosed included hypoplasia of either ventricle, common atrioventricular canal, tetralogy of Fallot, transposition of the great vessels, and Ebstein anomaly. Defects rarely diagnosed correctly included semilunar valve stenosis, total anomalous pulmonary venous drainage, coarctation of the aorta, pulmonic atresia, atrioseptal defect, and ventricular septal defect. Many types of heart defects can be diagnosed accurately with prenatal US in a general population of patients not at high risk for congenital heart disease. Some lesions, however, were difficult to detect.
在一组连续接受产前超声（US）检查的患者中，研究了产前超声检测结构性心脏缺陷的可靠性。在49例经体格检查或尸检显示有一个或多个心脏缺陷的胎儿中，有28例（57%）通过产前超声被发现患有先天性心脏病。49例胎儿共有66处心脏缺陷，其中33处（50%）被全部或部分识别。正确诊断的缺陷包括任一心室发育不全、房室通道共同管、法洛四联症、大动脉转位和埃布斯坦畸形。很少被正确诊断的缺陷包括半月瓣狭窄、完全性肺静脉异位引流、主动脉缩窄、肺动脉闭锁、房间隔缺损和室间隔缺损。在一般先天性心脏病低风险患者群体中，许多类型的心脏缺陷可以通过产前超声准确诊断。然而，一些病变很难检测到。
