Center for Program Development, Implementation, Research and Evaluation, AIDS Institute, New York State Department of Health, Albany, NY.
University at Albany School of Public Health, State University at New York, Rensselaer, NY.
J Acquir Immune Defic Syndr. 2023 Jun 1;93(2):92-100. doi: 10.1097/QAI.0000000000003177. Epub 2023 Feb 21.
Persons living with diagnosed HIV (PLWDH) have higher COVID-19 diagnoses rates and poorer COVID-19-related outcomes than persons living without diagnosed HIV. The intersection of COVID-19 vaccination status and likelihood of severe COVID-19 outcomes has not been fully investigated for PLWDH.
New York State (NYS).
We matched HIV surveillance, immunization, and hospitalization databases to compare COVID-19 vaccination and COVID-19-related hospitalizations among PLWDH during B.1.617.2 (Delta) and B.1.1.529 (Omicron) predominance.
Through March 4, 2022, 69,137 of the 101,205 (68%) PLWDH were fully vaccinated or boosted for COVID-19. PLWDH who were virally suppressed or in care were more often to be fully vaccinated or boosted compared with PLWDH who were not virally suppressed (77% vs. 44%) or without evidence of care (74% vs. 33%). Overall hospitalization rates were lower among virally suppressed PLWDH. During Delta predominance, PLWDH with any vaccination history who were in care had lower hospitalization rates compared with those not in care; during Omicron predominance, this was the case only for boosted PLWDH.
Approximately 28% (28,255) of PLWDH in NYS remained unvaccinated for COVID-19, a rate roughly double of that observed in the overall adult NYS population. PLWDH of color were more often than non-Hispanic White persons to be unvaccinated, as were the virally unsuppressed and those without evidence of HIV-related care, threatening to expand existing disparities in COVID-19-related outcomes. Vaccination was protective against COVID-19-related hospitalizations for PLWDH; however, differences in hospitalization rates between fully vaccinated and unvaccinated PLWDH were smaller than those among all New Yorkers.
已确诊 HIV 的感染者（PLWDH）的 COVID-19 诊断率和 COVID-19 相关结局较未确诊 HIV 的感染者更高。PLWDH 中 COVID-19 疫苗接种状况和严重 COVID-19 结局的可能性的交集尚未得到充分研究。
纽约州（NYS）。
我们将 HIV 监测、免疫和住院数据库进行匹配，以比较 B.1.617.2（Delta）和 B.1.1.529（Omicron）流行期间 PLWDH 的 COVID-19 疫苗接种和 COVID-19 相关住院情况。
截至 2022 年 3 月 4 日，在 101,205 名 PLWDH 中，有 69,137 名（68%）完全接种或加强了 COVID-19 疫苗。与未受抑制病毒（74%对 33%）或未进行 HIV 护理（74%对 33%）的 PLWDH 相比，受抑制病毒或正在接受护理的 PLWDH 更常完全接种或加强疫苗（77%对 44%）。受抑制病毒的 PLWDH 的总体住院率较低。在 Delta 流行期间，有任何疫苗接种史且正在接受护理的 PLWDH 的住院率低于未接受护理的 PLWDH；在 Omicron 流行期间，这种情况仅适用于加强免疫的 PLWDH。
纽约州约有 28%（28,255 名）的 PLWDH 未接种 COVID-19 疫苗，这一比例几乎是纽约州所有成年人的两倍。与非西班牙裔白人相比，有色人种的 PLWDH 更常未接种疫苗，未受抑制病毒的 PLWDH 和未进行 HIV 护理的 PLWDH 也是如此，这有可能扩大 COVID-19 相关结局方面现有的差异。疫苗接种对 PLWDH 的 COVID-19 相关住院有保护作用；然而，完全接种疫苗和未接种疫苗的 PLWDH 之间的住院率差异小于所有纽约人的差异。
