Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei, China (mainland).
Med Sci Monit. 2023 Mar 1;29:e938823. doi: 10.12659/MSM.938823.
BACKGROUND Postpartum hemorrhage (PPH) may be primary or secondary and is defined as the loss of 500 ml or more of blood within the first 24 h after birth. The Bakri balloon tamponade (BBT) is an intrauterine device used as an adjunctive treatment for refractory PPH. The aim of this study was to present the real-world experience from a single center on the effectiveness of the BBT for the treatment of PPH. MATERIAL AND METHODS This cohort study of 279 women was conducted in a real-world setting. Patients' characteristics and clinical outcomes between the BBT Success group and BBT Failure group were analyzed by t test or chi-square test. The primary outcome was the success rate of BBT. The secondary outcomes were the perinatal outcomes. RESULTS The success rate of BBT was 88.89% (248/279). A blood transfusion rate of 65.95% (184/279) was observed. After using the BBT, significant differences were observed in intervention (P<0.001), blood loss (P<0.001), indwelling time of BBT (P<0.001), and blood transfusion (P<0.001) between the Success group and Failure group. The Success group showed greater range of descent in blood loss (991.56.15±13.65 mL in Success group vs 816.23±7.57 mL in Failure group). Of the 31 women with BBT failure, 87.10% (27/31) received uterine artery embolization (UAE), 96.77% (30/31) received blood transfusion, and none required a hysterectomy. CONCLUSIONS The findings from this study from a single center in China supported those from previous studies showing that the BBT was an effective treatment to control PPH.
产后出血（PPH）可分为原发性或继发性，是指产后 24 小时内失血 500 毫升或以上。Bakri 球囊填塞（BBT）是一种宫内装置，用作难治性 PPH 的辅助治疗。本研究旨在介绍单中心对 BBT 治疗 PPH 的有效性的真实世界经验。
这是一项在真实环境中进行的 279 名妇女的队列研究。通过 t 检验或卡方检验分析 BBT 成功组和 BBT 失败组患者的特征和临床结局。主要结局是 BBT 的成功率。次要结局是围产期结局。
BBT 的成功率为 88.89%（248/279）。观察到 279 名患者中有 65.95%（184/279）需要输血。使用 BBT 后，成功组和失败组在干预（P<0.001）、出血量（P<0.001）、BBT 留置时间（P<0.001）和输血（P<0.001）方面差异有统计学意义。成功组的出血量下降幅度更大（991.56.15±13.65 毫升 vs 816.23±7.57 毫升）。在 31 名 BBT 失败的患者中，87.10%（27/31）接受了子宫动脉栓塞术（UAE），96.77%（30/31）接受了输血，无一例需要子宫切除术。
本研究结果来自中国的单中心，支持了先前研究的结果，表明 BBT 是控制 PPH 的有效治疗方法。
