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继发于化脓性肝脓肿的急性肝衰竭

Acute Liver Failure Secondary to Pyogenic Hepatic Abscess.

作者信息

Elmusa Emad, Raza Muhammad Waleed, Orlando Michael, Boyd Seth, Kulchinsky Robert

机构信息

Internal Medicine, HCA Florida (FL) Orange Park Hospital, Orange Park, USA.

Transitional Year (TY), HCA Florida (FL) Orange Park Hospital, Orange Park, USA.

出版信息

Cureus. 2023 Jan 27;15(1):e34258. doi: 10.7759/cureus.34258. eCollection 2023 Jan.

DOI:10.7759/cureus.34258
PMID:36855481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9968402/
Abstract

Hepatic abscesses are rare and can be pyogenic or amebic. Pyogenic hepatic abscesses are treated with antibiotics, percutaneous drainage when larger than 5 cm, and rarely requires surgical treatment. Clinical and laboratory manifestations of pyogenic hepatic abscesses include fever, abdominal pain, and elevations in liver enzymes. There is little documentation that a pyogenic hepatic abscess can cause acute liver failure. We present a case of a patient who developed acute liver failure secondary to a 14 cm pyogenic liver abscess. The patient's hepatic function normalized with percutaneous drain placement and antibiotics.

摘要

肝脓肿较为罕见,可分为化脓性和阿米巴性。化脓性肝脓肿采用抗生素治疗,脓肿直径大于5厘米时进行经皮引流,很少需要手术治疗。化脓性肝脓肿的临床和实验室表现包括发热、腹痛和肝酶升高。目前鲜有文献记载化脓性肝脓肿可导致急性肝衰竭。我们报告一例因14厘米的化脓性肝脓肿继发急性肝衰竭的患者。经皮置管引流和使用抗生素后,患者肝功能恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/db005a7a2913/cureus-0015-00000034258-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/6bf9555772e5/cureus-0015-00000034258-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/51d129d1d400/cureus-0015-00000034258-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/b5b281e47ed6/cureus-0015-00000034258-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/805e8fddb3cd/cureus-0015-00000034258-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/5308e9ffc733/cureus-0015-00000034258-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/d84bee9aabcb/cureus-0015-00000034258-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/21f38b515754/cureus-0015-00000034258-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/7e1fedfdf03b/cureus-0015-00000034258-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/a0e78441f1f3/cureus-0015-00000034258-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/db005a7a2913/cureus-0015-00000034258-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/6bf9555772e5/cureus-0015-00000034258-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/51d129d1d400/cureus-0015-00000034258-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/b5b281e47ed6/cureus-0015-00000034258-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/805e8fddb3cd/cureus-0015-00000034258-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/5308e9ffc733/cureus-0015-00000034258-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/d84bee9aabcb/cureus-0015-00000034258-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/21f38b515754/cureus-0015-00000034258-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/7e1fedfdf03b/cureus-0015-00000034258-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/a0e78441f1f3/cureus-0015-00000034258-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb26/9968402/db005a7a2913/cureus-0015-00000034258-i10.jpg

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Pyogenic and Amebic Infections of the Liver.肝化脓性和阿米巴性感染。
Gastroenterol Clin North Am. 2020 Jun;49(2):361-377. doi: 10.1016/j.gtc.2020.01.013.
2
Evaluation of the Effect of Apixaban on INR in the Inpatient Population.评估阿哌沙班对住院患者 INR 的影响。
J Cardiovasc Pharmacol Ther. 2019 Jul;24(4):355-358. doi: 10.1177/1074248419838502. Epub 2019 Mar 24.
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Hepatic Encephalopathy: Definition, Clinical Grading and Diagnostic Principles.肝性脑病:定义、临床分级和诊断原则。
Drugs. 2019 Feb;79(Suppl 1):5-9. doi: 10.1007/s40265-018-1018-z.
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Hepatic abscess: Diagnosis and management.肝脓肿:诊断与管理
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Percutaneous needle aspiration versus catheter drainage in the management of liver abscess: a systematic review and meta-analysis.经皮针吸术与导管引流术治疗肝脓肿的系统评价和荟萃分析
HPB (Oxford). 2015 Mar;17(3):195-201. doi: 10.1111/hpb.12332. Epub 2014 Sep 10.
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Acute liver failure.急性肝衰竭
N Engl J Med. 2013 Dec 26;369(26):2525-34. doi: 10.1056/NEJMra1208937.