Abdul-Amir I M, Gray J S
Department of Agricultural Zoology and Genetics, University College, Belfield, Dublin.
Res Vet Sci. 1987 Sep;43(2):266-7.
The development of tick resistance was studied in three one-year-old female Galway cross ewes which received up to three staggered infestations of 100 adult pairs of Ixodes ricinus. Sheep acquired resistance after the first infestation and the ticks showed suppressed feeding and oviposition success. The histology of tick-bite lesions revealed a cellular infiltrate consisting predominantly of neutrophils and this was followed by the infiltration and degranulation of basophils. Mononuclear cells accompanied basophil infiltration and then dominated the cellular infiltrate. Eosinophils infiltrated tick-bite lesions in considerable numbers especially in the tertiary infestation, in which degranulation of mast cells and basophils was also most rapid.
在三只一岁的戈尔韦杂交母羊中研究了蜱抗性的发展情况，这些母羊接受了多达三次错开的100对成年蓖麻硬蜱的侵染。绵羊在第一次侵染后获得了抗性，蜱的取食和产卵成功率受到抑制。蜱叮咬损伤的组织学检查显示，细胞浸润主要由中性粒细胞组成，随后是嗜碱性粒细胞的浸润和脱颗粒。单核细胞伴随嗜碱性粒细胞浸润，然后在细胞浸润中占主导地位。嗜酸性粒细胞大量浸润蜱叮咬损伤部位，尤其是在第三次侵染时，肥大细胞和嗜碱性粒细胞的脱颗粒也最为迅速。
