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一枚未进行抗凝治疗36年后仍功能良好的比约克-希利主动脉瓣。

A functioning Björk-Shiley aortic valve after 36 years without anticoagulation.

作者信息

Helms Florian, Rosebrock Frauke, Haverich Axel, Rustum Saad

机构信息

Division of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

出版信息

Interdiscip Cardiovasc Thorac Surg. 2023 Feb 6;36(2). doi: 10.1093/icvts/ivad029.

Abstract

There is a broad consensus among all clinical guidelines that lifelong oral anticoagulation is mandatory after mechanical valve prosthesis implantation. However, in rare cases, patients do not receive anticoagulation or anticoagulation therapy is withdrawn over time. We present a case of an exceptionally durable Björk-Shiley mechanical aortic valve prosthesis still functioning 49 years after implantation. Remarkably, the patient did not receive any anticoagulation or antiplatelet therapy for the first 36 years after implantation. Despite this, no thromboembolic or valve-related adverse events occurred to date. Upon thorough echocardiographic assessment, excellent valve function with a mean transvalvular gradient of 13 mmHg and no prosthetic valve insufficiency was found. This makes the case presented here one of the longest functioning mechanical valve replacements reported.

摘要

所有临床指南都达成了广泛共识,即机械瓣膜置换术后必须进行终身口服抗凝治疗。然而,在极少数情况下,患者未接受抗凝治疗或随着时间推移抗凝治疗被停用。我们报告了一例极为耐用的 Björk-Shiley 机械主动脉瓣膜置换术病例,该瓣膜在植入后 49 年仍在发挥功能。值得注意的是,患者在植入后的前 36 年未接受任何抗凝或抗血小板治疗。尽管如此,迄今为止未发生血栓栓塞或瓣膜相关不良事件。经全面超声心动图评估,发现瓣膜功能良好,平均跨瓣压差为 13 mmHg,且无人工瓣膜关闭不全。这使得此处报告的病例成为已报道的功能持续时间最长的机械瓣膜置换病例之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/9976733/c3889b668ff1/ivad029f1.jpg

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