Vazquez F, Mendez F J, Perez F, Mendoza M C
Departamento Interfacultativo de Microbiologia, Universidad de Oviedo, Spain.
Rev Infect Dis. 1987 Sep-Oct;9(5):1038-43. doi: 10.1093/clinids/9.5.1038.
Anaerobic bacteremia (116 cases) represented 5.4% of the total cases of bacteremia in the Hospital Nuestra Señora de Covadonga of Oviedo, Spain, during a five-year period (1981-1985). Microbiologic data for all 116 cases and clinical data for 63 patients were analyzed. A total of 129 isolates were identified as gram-negative bacilli (45.7%), gram-positive bacilli (38.0%), gram-positive cocci (14.0%), and gram-negative cocci (2.3%). Bacteroides fragilis and Clostridium perfringens were the most frequently occurring species. Anaerobic polymicrobial infection was detected in 21 patients. The most relevant clinical features were fever (79%), metastatic abscesses (33%), anemia (27%), septic shock (25%), and disseminated intravascular coagulation (6%). The overall mortality rate was 25.4%, and the factors associated with a poor prognosis were age over 60 years, lack of adequate surgical treatment, severe underlying disease, metastatic foci, and polymicrobial and/or nosocomial infection.
在西班牙奥维耶多的科瓦东加圣母医院，五年期间（1981 - 1985年），厌氧菌血症（116例）占菌血症总病例数的5.4%。分析了所有116例的微生物学数据以及63例患者的临床数据。共鉴定出129株分离菌，其中革兰氏阴性杆菌（45.7%）、革兰氏阳性杆菌（38.0%）、革兰氏阳性球菌（14.0%）和革兰氏阴性球菌（2.3%）。脆弱拟杆菌和产气荚膜梭菌是最常见的菌种。21例患者检测到厌氧多微生物感染。最相关的临床特征为发热（79%）、转移性脓肿（33%）、贫血（27%）、感染性休克（25%）和弥散性血管内凝血（6%）。总体死亡率为25.4%，与预后不良相关的因素为年龄超过60岁、缺乏充分的手术治疗、严重的基础疾病、转移灶以及多微生物和/或医院感染。
