Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8553, Japan; Department of Neurosurgery, Itsukaichi Memorial Hospital, Seifu Health Care Group, Kurashige 1-95, Saeki-ku, Hiroshima, 731-5156, Japan.
Division of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8553, Japan.
Neurosci Lett. 2023 Mar 28;801:137160. doi: 10.1016/j.neulet.2023.137160. Epub 2023 Feb 27.
The electroencephalogram and magnetic field primary somatosensory cortex (S1)-derived components are attenuated before and during motor tasks compared to the resting state, a phenomenon called gating; however, the S1 response after a motor task has not been well studied. We aimed to investigate sensory information processing immediately after motor tasks using magnetoencephalography.
We investigated sensory information processing immediately after finger movement using magnetoencephalography in 14 healthy adults. Volunteers performed a simple reaction task where they were required to press a button when they received a cue. In parallel, electrical stimulation to the right index finger was applied at regular intervals to detect the magnetic brain field changes. The end of the motor task timing was defined using the event-related synchronization (ERS) appearance latency in the brain magnetic field's beta band around the primary motor cortex. The ERS appearance latency and the sensory stimuli timing applied every 500 ms were synchronized over the experimental system timeline. We examined whether there was a difference in the S1 somatosensory evoked field responses between the ERS emergence and ERS disappearance phase, focusing on the N20m-P35m peak-to-peak amplitude (N20m-P35m amplitude) value. A control experiment was also conducted in which only sensory stimulation was applied with no motor task.
The N20m-P35m mean amplitude value was significantly higher in the ERS emergence phase (15.81 nAm; standard deviation [SD], 6.54 nAm) than in the ERS disappearance phase (13.54 nAm; SD, 5.12 nAm) (p < 0.05) and the control (12.08 nAm, SD 5.61 nAm) (p = 0.013). No statistically significant differences were identified between the ERS disappearance phase and the control (p = 0.281).
The S1 sensitivity may increase rapidly after exiting from the gating influence in S1 (after completing a motor task).
与静息状态相比，在运动任务之前和期间，脑电图和磁场初级体感皮层（S1）衍生成分会减弱，这种现象称为门控；然而，运动任务后的 S1 反应尚未得到很好的研究。我们旨在使用脑磁图研究运动任务后立即的感觉信息处理。
我们使用 14 名健康成年人的脑磁图研究了手指运动后立即的感觉信息处理。志愿者执行了一个简单的反应任务，当他们收到提示时，他们需要按下按钮。同时，以规则的时间间隔向右手食指施加电刺激，以检测磁场变化。运动任务结束时间的定义是基于大脑磁场在初级运动皮层周围β频带的事件相关同步（ERS）出现潜伏期。运动任务结束时间的定义是基于大脑磁场在初级运动皮层周围β频带的事件相关同步（ERS）出现潜伏期。在实验系统时间线上，大脑磁场的 ERS 出现潜伏期和每个 500 ms 施加的感觉刺激时间同步。我们检查了在 ERS 出现和 ERS 消失阶段之间，S1 体感诱发电场反应是否存在差异，重点关注 N20m-P35m 峰-峰幅度（N20m-P35m 幅度）值。还进行了一项对照实验，其中仅施加感觉刺激，而不进行运动任务。
N20m-P35m 的平均幅度值在 ERS 出现阶段（15.81 nAm；标准差 [SD]，6.54 nAm）显著高于 ERS 消失阶段（13.54 nAm；SD，5.12 nAm）（p < 0.05）和对照（12.08 nAm，SD 5.61 nAm）（p = 0.013）。ERS 消失阶段与对照之间无统计学差异（p = 0.281）。
S1 敏感性可能在 S1 门控影响消失后（完成运动任务后）迅速增加。
