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使用小型史托斯-霍普金斯支气管镜时的呼吸性酸中毒:发生率及处理

Respiratory acidosis with the small Storz-Hopkins bronchoscopes: occurrence and management.

作者信息

Rah K H, Salzberg A M, Boyan C P, Greenfield L J

出版信息

Ann Thorac Surg. 1979 Mar;27(3):197-202. doi: 10.1016/s0003-4975(10)63274-2.

DOI:10.1016/s0003-4975(10)63274-2
PMID:36859
Abstract

Carbon dioxide retention in the Storz rigid ventilating bronchoscope with the Hopkins lens system was investigated in the laboratory. The 3.5, 4.0, and 5.0 30-cm Storz bronchoscopes with a 3.95-mm (outside diameter) telescope lens were used in 10 mongrel dogs weighing between 8 and 15 kg. Significant (p less than 0.01) accumulation of arterial carbon dioxide tension (PaCO2) (respiratory acidosis) was observed after 5 and 10 minutes of ventilation through the 3.5 and 4.0 bronchoscopes, but no significant increase in PaCO2 was noted with the 5.0 bronchoscope. There was no significant change in arterial oxygen tension under the same conditions. Manual compression of the upper anterior abdominal wall during expiration was applied during bronchoscopy in 6 children. Arterial blood samples were taken before insertion of the bronchoscope and 5 minutes later with and without abdominal compression during expiration. A significant increase (p less than 0.05) in PaCO2 and a decrease in pH were observed after 5 minutes of the bronchoscopic procedure without manual compression of the abdominal wall, while no significant changes in PaCO2 were observed with abdominal compression.

摘要

在实验室中对配备Hopkins透镜系统的Storz硬质通气支气管镜中的二氧化碳潴留情况进行了研究。使用了外径为3.95毫米的30厘米长的3.5、4.0和5.0 Storz支气管镜,对10只体重在8至15千克之间的杂种犬进行实验。在通过3.5和4.0支气管镜通气5分钟和10分钟后,观察到动脉血二氧化碳分压(PaCO2)显著(p小于0.01)升高(呼吸性酸中毒),但使用5.0支气管镜时未发现PaCO2有显著升高。在相同条件下,动脉血氧分压无显著变化。对6名儿童进行支气管镜检查时,在呼气时手动按压上腹部前壁。在插入支气管镜前以及支气管镜检查5分钟后,分别在呼气时有无腹部按压的情况下采集动脉血样本。在支气管镜检查5分钟且未进行腹部按压时,观察到PaCO2显著升高(p小于0.05)且pH值降低,而在进行腹部按压时,PaCO2未观察到显著变化。

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