Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland.
Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland
Pol Arch Intern Med. 2023 Aug 30;133(7-8). doi: 10.20452/pamw.16450. Epub 2023 Feb 28.
Although it is well‑known that longer electrocardiographic (ECG) monitoring allows for detection of paroxysmal silent atrial fibrillation (SAF), it is still unknown how long the ECG monitoring should last to increase the probability of SAF diagnosis.
Our aim was to analyze ECG acquisition parameters and timing to detect SAF during the Noninvasive Monitoring for Early Detection of Atrial Fibrillation study.
The protocol assumed up to 30 days of ECG telemonitoring of each participant in order to reveal AF / atrial flutter (AFL) episodes lasting at least 30 seconds. SAF was defined as AF detected and confirmed by cardiologists in asymptomatic individuals. The ECG signal analysis was based on the results of 2974 participants (98.67%). AF/AFL episodes were registered and confirmed by cardiologists in 515 individuals, that is, 75.7% of all patients (n = 680) in whom AF/AFL diagnosis was established.
The median monitoring time to detect the first SAF episode was 6 days (interquartile range [IQR], 1-13). Fifty percent of the patients with this type of arrhythmia were identified by 6th day (IQR, 1-13) of the monitoring, and 75% by the 13th day of the study. Paroxysmal AF was registered on average on 4th day (IQR, 1-10).
The ECG monitoring time to detect the first episode of SAF in at least 75% of patients at risk of this arrhythmia was 14 days. Detection of 1 patient with de novo AF, SAF, or de novo SAF, required monitoring of, respectively, 17, 11, and 23 patients.
尽管众所周知,更长时间的心电图(ECG)监测可以检测到阵发性无症状性心房颤动(SAF),但仍不清楚 ECG 监测需要多长时间才能增加 SAF 诊断的可能性。
我们的目的是分析非侵入性监测早期心房颤动研究中检测 SAF 的心电图采集参数和时间。
该方案假设每个参与者的心电图远程监测最长可达 30 天,以便发现持续至少 30 秒的 AF/心房扑动(AFL)发作。无症状个体中由心脏病专家检测和确认的 SAF 定义为 AF。心电图信号分析基于 2974 名参与者(98.67%)的结果。在 515 名患者(即所有确诊 AF/AFL 患者中的 75.7%,n=680)中,AF/AFL 发作由心脏病专家记录并确认。
首次 SAF 发作的中位监测时间为 6 天(四分位间距 [IQR],1-13)。50%的此类心律失常患者在监测的第 6 天(IQR,1-13)被识别,75%的患者在第 13 天被识别。阵发性 AF 平均在第 4 天(IQR,1-10)被记录。
在至少 75%有此类心律失常风险的患者中,检测首次 SAF 发作的心电图监测时间为 14 天。检测 1 例新发 AF、SAF 或新发 SAF 分别需要监测 17、11 和 23 例患者。