Eren Eryiğit, Tokaç Mehmet, Uslu Bora, Şahin Taylan, Vartanoğlu Aktokmakyan Talar, Dinçkan Ayhan
Department of General Surgery, Istinye University Training and Research Hospital, İstanbul, Turkey.
Department of Internal Medicine, Division of Nephrology, İstinye University Training and Research Hospital, İstanbul, Turkey.
Eurasian J Med. 2023 Feb;55(1):74-77. doi: 10.5152/eurasianjmed.2022.0259.
Although it was postulated that renal grafts with multiple arteries could lead to unfavorable recipient outcomes, this subject remains controversial. This study aimed to compare the outcomes of recipients receiving renal allografts with a single artery with those receiving renal grafts with two arteries.
Adult patients who received live donor kidney transplantation in our center between January 2020 and October 2021 were included. Data including age, gender, body mass index, renal allograft side, pre-kidney transplantation dialysis status, human leukocyte antigen mismatch number, warm ischemia time, the number of renal allograft arteries (single/double), complications, duration of hospitalization, postoperative creatinine levels, glomerular filtration rates, early graft rejection, graft loss, and mortality were collected. Subsequently, patients who received single-artery renal allografts were compared with those who received double-artery renal allografts.
Overall, 139 recipients were included. The mean recipient age was 43.73 ± 13.03 (21-69). While 103 recipients were male, 36 were female. The comparison between the 2 groups revealed that mean ischemia time was significantly longer in the double-artery than in the single-artery group (48.0 vs. 31.2 minutes) (P=.00). In addition, the single-artery group had significantly lower postoperative day 1 and day 30 mean serum creatinine levels. Also, the mean postoperative day 1 glomerular filtration rates were significantly higher in the single-artery group than in the double-artery group. However, the 2 groups were similar concerning the glomerular filtration rates measured at other times. On the other hand, there was no difference between the 2 groups regarding duration of hospitalization, surgical complication, early graft rejection, graft loss, and mortality rates.
The presence of 2 renal allograft arteries does not have adverse effects on the postoperative parameters of the kidney transplantation recipients, including graft function, duration of hospitalization, surgical complication, early graft rejection, graft loss, and mortality rates.
尽管有人推测具有多条动脉的肾移植可能导致受者出现不良结局，但这一问题仍存在争议。本研究旨在比较接受单动脉肾移植的受者与接受双动脉肾移植的受者的结局。
纳入2020年1月至2021年10月在本中心接受活体供肾移植的成年患者。收集的数据包括年龄、性别、体重指数、肾移植侧别、肾移植前透析状态、人类白细胞抗原错配数、热缺血时间、肾移植动脉数量（单/双）、并发症、住院时间、术后肌酐水平、肾小球滤过率、早期移植肾排斥反应、移植肾丢失和死亡率。随后，将接受单动脉肾移植的患者与接受双动脉肾移植的患者进行比较。
总体而言，共纳入139名受者。受者的平均年龄为43.73±13.03岁（21 - 69岁）。其中男性103名，女性36名。两组比较显示，双动脉组的平均缺血时间明显长于单动脉组（48.0分钟对31.2分钟）（P = 0.00）。此外，单动脉组术后第1天和第30天的平均血清肌酐水平明显更低。而且，单动脉组术后第1天的平均肾小球滤过率明显高于双动脉组。然而，在其他时间点测量的肾小球滤过率方面，两组相似。另一方面，两组在住院时间、手术并发症、早期移植肾排斥反应、移植肾丢失和死亡率方面没有差异。
肾移植存在两条动脉对肾移植受者的术后参数，包括移植肾功能、住院时间、手术并发症、早期移植肾排斥反应、移植肾丢失和死亡率，没有不良影响。
