Meyer E C, Schoeman H S
Department of Pharmacology, University of Pretoria.
S Afr Med J. 1987 Nov 21;72(10):663-5.
In an open uncontrolled trial 60 women with confirmed uncomplicated urinary tract infections were randomly allocated to receive either pipemidic acid (Septidron; Ethimed) or nitrofurantoin for 10 days. Urine cultures were done on day 1 and day 10. No statistical difference was found in the subjective and objective assessments of the response to the two medications and it is concluded that pipemidic acid is a satisfactory and effective alternative to nitrofurantoin in the treatment of uncomplicated urinary tract infections in women.
在一项开放性非对照试验中，60名确诊为单纯性尿路感染的女性被随机分配接受吡哌酸（Septidron；Ethimed）或呋喃妥因治疗10天。在第1天和第10天进行尿培养。对两种药物反应的主观和客观评估未发现统计学差异，得出结论：在治疗女性单纯性尿路感染方面，吡哌酸是呋喃妥因令人满意且有效的替代药物。
