巴西糖尿病视网膜病变的患病率：一项荟萃分析的系统评价
Prevalence of diabetic retinopathy in Brazil: a systematic review with meta-analysis.
作者信息
Chagas Thiago Alves, Dos Reis Mateus Augusto, Leivas Gabriel, Santos Lucas Porto, Gossenheimer Agnes Nogueira, Melo Gustavo Barreto, Malerbi Fernando Korn, Schaan Beatriz D
机构信息
Instituto de Olhos Cristiano Mendonça, Aracaju, SE, Brazil.
Graduate Program in Medical Sciences: Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
出版信息
Diabetol Metab Syndr. 2023 Mar 2;15(1):34. doi: 10.1186/s13098-023-01003-2.
AIMS
To evaluate the prevalence of diabetic retinopathy (DR) in Brazilian adults with diabetes mellitus via a systematic review with meta-analysis.
METHODS
A systematic review using PubMed, EMBASE, and Lilacs was conducted, searching for studies published up to February 2022. Random effect meta-analysis was performed to estimate the DR prevalence.
RESULTS
We included 72 studies (n = 29,527 individuals). Among individuals with diabetes in Brazil, DR prevalence was 36.28% (95% CI 32.66-39.97, I 98%). Diabetic retinopathy prevalence was highest in patients with longer duration of diabetes and in patients from Southern Brazil.
CONCLUSION
This review shows a similar prevalence of DR as compared to other low- and middle-income countries. However, the high heterogeneity observed-expected in systematic reviews of prevalence-raises concerns about the interpretation of these results, suggesting the need for multicenter studies with representative samples and standardized methodology.
目的
通过系统评价和荟萃分析评估巴西成年糖尿病患者糖尿病视网膜病变（DR）的患病率。
方法
利用PubMed、EMBASE和Lilacs进行系统评价，检索截至2022年2月发表的研究。采用随机效应荟萃分析来估计DR患病率。
结果
我们纳入了72项研究（n = 29527人）。在巴西糖尿病患者中，DR患病率为36.28%（95%CI 32.66 - 39.97，I² 98%）。糖尿病视网膜病变患病率在糖尿病病程较长的患者以及巴西南部患者中最高。
结论
本评价显示，与其他低收入和中等收入国家相比，DR患病率相似。然而，在患病率的系统评价中观察到的高异质性——这在这类评价中是预期的——引发了对这些结果解读的担忧，表明需要开展具有代表性样本和标准化方法的多中心研究。
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