Oranje A P, Peereboom-Wynia J D, de Raeymaecker D M
Afd. Dermatovenereologie, Erasmus Universiteit, Sophia Kinderziekenhuis/Academisch Ziekenhuis Rotterdam.
Tijdschr Kindergeneeskd. 1987 Oct;55(5):177-81.
Alopecia areata is a hair disease of unknown origin characterized by the sudden appearance of one or more bald patches. This disorder may develop in adults as well as in children. In childhood there is often an association with atopy. Most investigators feel that alopecia areata is an auto-immune phenomenon with heterogeneous aetiology. This article deals with hypotheses for the development of alopecia areata stressing also the psychosomatic aspects. Different therapy modalities have been propagated in alopecia areata, though complete satisfactory effects have been achieved by none. In childhood application of dithranol and locally applied corticosteroids are the only suitable therapeutic possibilities. Insufficient insight into the pathogenesis and associations of this disorder in childhood warrants further investigations.
斑秃是一种病因不明的毛发疾病，其特征为突然出现一个或多个秃斑。这种疾病在成人和儿童中均可发生。在儿童期，斑秃常与特应性疾病相关。大多数研究者认为斑秃是一种病因多样的自身免疫现象。本文探讨了斑秃发病的假说，同时也强调了身心方面的因素。斑秃有多种不同的治疗方式，但目前尚无一种能取得完全令人满意的效果。在儿童期，蒽林的应用以及局部使用皮质类固醇是仅有的合适治疗方法。对儿童斑秃发病机制及相关因素的认识不足，需要进一步研究。
