Sydney Southeast Asia Centre, University of Sydney, Sydney, New South Wales, Australia.
Am J Biol Anthropol. 2023 Jun;181(2):326-335. doi: 10.1002/ajpa.24721. Epub 2023 Mar 3.
Weighted threshold diagnostic criteria approaches have emerged for diseases that involve skeletal/bony tissue that are readily diagnosed in the field of paleopathology such as Vitamin C deficiency (scurvy), Vitamin D deficiency (rickets) and treponemal disease. These criteria differ from traditional differential diagnosis in that they involve standardized inclusion criteria based on the lesion's specificity to the disease. Here I discuss the limitations and benefits of threshold criteria. I argue that while these criteria will benefit from further revision such as inclusion of lesion severity, and the incorporation of exclusion criteria, threshold diagnostic approaches have considerable value in the future of diagnosis in the field.
加权阈值诊断标准方法已经出现，适用于骨骼组织疾病，这些疾病在古病理学领域很容易诊断，如维生素 C 缺乏症（坏血病）、维生素 D 缺乏症（佝偻病）和梅毒病。这些标准与传统的鉴别诊断不同，因为它们涉及基于病变对疾病的特异性的标准化纳入标准。在这里，我将讨论阈值标准的局限性和优势。我认为，尽管这些标准将受益于进一步修订，例如纳入病变严重程度，并纳入排除标准，但阈值诊断方法在该领域的未来诊断中具有相当大的价值。
