VCA ASEC, Los Angeles, CA.
Department of Molecular Biomedical Sciences, NC State College of Veterinary Medicine, Raleigh, NC.
Vet Radiol Ultrasound. 2023 May;64(3):537-545. doi: 10.1111/vru.13227. Epub 2023 Mar 3.
Ultrasonography is the most commonly used diagnostic imaging tool for gallbladder disease in veterinary medicine. Primary gallbladder neoplasia is an uncommon finding with variable prognosis for which no studies have been published describing their ultrasonographic appearance and diagnosis. This retrospective, multicenter, case series study examines the ultrasonographic appearance of gallbladder neoplasia with histologically or cytologically confirmed diagnoses. A total of 14 dogs and 1 cat were analyzed. All discrete masses were sessile in shape and varied in size, echogenicity, location, and gallbladder wall thickening. All studies with images showing Doppler interrogation exhibited vascularity. Cholecystoliths were an uncommon finding, being present in only one case in this study, unlike in humans. The final diagnosis of the gallbladder neoplasia was neuroendocrine carcinoma (8), leiomyoma (3), lymphoma (1), gastrointestinal stromal tumor (1), extrahepatic cholangiocellular carcinoma (1), and adenoma (1). Findings from this study indicate that primary gallbladder neoplasms have variable sonographic appearances and cytologic and histologic diagnoses.
超声检查是兽医界用于诊断胆囊疾病最常用的影像学方法。原发性胆囊肿瘤是一种不常见的疾病,其预后因缺乏描述其超声表现和诊断的研究而有所不同。本回顾性多中心病例系列研究检查了经组织学或细胞学证实的胆囊肿瘤的超声表现。共分析了 14 只狗和 1 只猫。所有离散性肿块均为无蒂状,大小、回声、位置和胆囊壁增厚各不相同。所有显示多普勒检查的研究均显示有血管。不同于人类,本研究中仅 1 例存在胆石症,胆石症较为少见。胆囊肿瘤的最终诊断为神经内分泌癌(8 例)、平滑肌瘤(3 例)、淋巴瘤(1 例)、胃肠道间质瘤(1 例)、肝外胆管细胞癌(1 例)和腺瘤(1 例)。本研究结果表明,原发性胆囊肿瘤的超声表现和细胞学及组织学诊断存在差异。