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澳大利亚全科医疗中未控制血压的成本:使用电子健康记录的建模研究(MedicineInsight)。

The Cost of Uncontrolled Blood Pressure in Australian General Practice: A Modelling Study Using Electronic Health Records (MedicineInsight).

机构信息

School of Public Health, Faculty of Health Sciences, The University of Adelaide, Adelaide, SA, Australia.

Discipline of General Practice, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.

出版信息

Pharmacoeconomics. 2023 May;41(5):573-587. doi: 10.1007/s40273-023-01251-0. Epub 2023 Mar 4.

Abstract

BACKGROUND

Hypertension is the most common condition seen in Australian general practice. Despite hypertension being amenable to lifestyle modifications and pharmacological treatment, only around half of these patients have controlled blood pressure levels (< 140/90 mmHg), placing them at an increased risk of cardiovascular disease.

OBJECTIVE

We aimed to estimate the health and acute hospitalisation costs of uncontrolled hypertension among patients attending general practice.

METHODS

We used population data and electronic health records from 634,000 patients aged 45-74 years who regularly attended an Australian general practice between 2016 and 2018 (MedicineInsight database). An existing worksheet-based costing model was adapted to calculate the potential cost savings for acute hospitalisation of primary cardiovascular disease events by reducing the risk of a cardiovascular event over the next 5 years through improved systolic blood pressure control. The model estimated the number of expected cardiovascular disease events and associated acute hospital costs under current levels of systolic blood pressure and compared this estimate with the expected number of cardiovascular disease events and costs under different levels of systolic blood pressure control.

RESULTS

The model estimated that across all Australians aged 45-74 years who visit their general practitioner (n = 8.67 million), 261,858 cardiovascular disease events can be expected over the next 5 years at current systolic blood pressure levels (mean 137.8 mmHg, standard deviation = 12.3 mmHg), with a cost of AUD$1813 million (in 2019-20). By reducing the systolic blood pressure of all patients with a systolic blood pressure greater than 139 mmHg to 139 mmHg, 25,845 cardiovascular disease events could be avoided with an associated reduction in acute hospital costs of AUD$179 million. If systolic blood pressure is lowered further to 129 mmHg for all those with systolic blood pressure greater than 129 mmHg, 56,169 cardiovascular disease events could be avoided with potential cost savings of AUD$389 million. Sensitivity analyses indicate that potential cost savings range from AUD$46 million to AUD$1406 million and AUD$117 million to AUD$2009 million for the two scenarios, respectively. Cost savings by practice range from AUD$16,479 for small practices to AUD$82,493 for large practices.

CONCLUSIONS

The aggregate cost effects of poor blood pressure control in primary care are high, but cost implications at the individual practice level are modest. The potential cost savings improve the potential to design cost-effective interventions, but such interventions may be best targeted at a population level rather than at individual practices.

摘要

背景

高血压是澳大利亚普通诊所最常见的病症。尽管高血压可以通过生活方式的改变和药物治疗来控制,但只有大约一半的患者血压水平得到了控制(<140/90mmHg),这使他们面临心血管疾病风险增加。

目的

我们旨在评估普通诊所就诊的未控制高血压患者的健康和急性住院费用。

方法

我们使用了来自 2016 年至 2018 年期间定期在澳大利亚普通诊所就诊的 634000 名 45-74 岁患者的人口数据和电子健康记录(MedicineInsight 数据库)。我们对现有的基于工作表的成本模型进行了改编,通过改善未来 5 年内的收缩压控制,降低心血管疾病一级事件的心血管事件风险,从而计算急性住院治疗原发性心血管疾病的潜在成本节约。该模型估计了在当前收缩压水平下预期发生的心血管疾病事件数量以及相关的急性住院费用,并将该估计与不同收缩压控制水平下预期发生的心血管疾病事件和费用进行了比较。

结果

该模型估计,在所有 45-74 岁的澳大利亚人中(n=867 万),在目前的收缩压水平下(平均收缩压 137.8mmHg,标准差=12.3mmHg),预计未来 5 年内将发生 261858 例心血管疾病事件,预计费用为 18.13 亿澳元(2019-20 年)。通过将所有收缩压大于 139mmHg 的患者的收缩压降低到 139mmHg,可以避免 25845 例心血管疾病事件,急性住院费用相应减少 1.79 亿澳元。如果将所有收缩压大于 129mmHg 的患者的收缩压进一步降低到 129mmHg,可以避免 56169 例心血管疾病事件,潜在节省费用 3.89 亿澳元。敏感性分析表明,对于这两种情况,潜在的节省成本范围分别为 4600 万澳元和 1.406 亿澳元至 14.06 亿澳元和 11.70 亿澳元至 2.009 亿澳元。实践中的成本节约从小型实践的 16479 澳元到大型实践的 82493 澳元不等。

结论

初级保健中血压控制不佳的总体成本影响很高,但在个体实践层面的成本影响是适度的。潜在的成本节约提高了设计具有成本效益的干预措施的可能性,但此类干预措施可能最好针对人群层面,而不是针对个别实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a8/10085904/179ece520738/40273_2023_1251_Fig1_HTML.jpg

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