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新冠病毒病康复患者的六个月发病率和死亡率

Six-month Morbidity and Mortality in Patients after Recovery from COVID-19.

作者信息

Rai Deependra Kumar, Sahay Nishant

机构信息

Department of Pulmonary Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.

Department of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India.

出版信息

Indian J Crit Care Med. 2022 Nov;26(11):1179-1183. doi: 10.5005/jp-journals-10071-24347.

Abstract

BACKGROUND

This telephonic survey was aimed to identify the proportion of coronavirus disease-2019 (COVID-19) patients who died from any cause, within 6 months of discharge from a tertiary COVID-19 care hospital. We also analyzed whether any clinical and/or laboratory variables were associated with post-discharge mortality.

MATERIALS AND METHODS

All adult patients (age ≥18 years) who had been discharged during the period between July 2020 and August 2020 from a tertiary COVID-19-care hospital after initial hospitalization for COVID-19 were included. A telephonic interview was conducted 6 months after discharge to assess morbidity and mortality in these patients.

RESULTS

Out of the 457 patients who responded, 79 patients (17.21%) were symptomatic, and breathlessness was found as most common symptom (6.12%). Fatigue was noted in (5.93%) of study patients, followed by cough (4.59%), sleep disturbances (4.37%), and headache (2.62%). Of the 457 patients who responded, 42 patients (9.19%) required expert medical consultation for their persistent symptoms. Thirty-six patients (7.88%) required re-hospitalization for post-COVID-19 complications within 6 months of discharge. A total of 10 patients (2.18%) succumbed within 6 months of their discharge from the hospital. 6 patients were males and 4 females. Most of these patients (7/10) succumbed in the second month after discharge. Seven patients had moderate-to-severe COVID-19 disease and most of these (7/10) had not been treated in the intensive care unit (ICU).

CONCLUSION

Post-COVID-19 mortality figures were not very high in our survey despite the high perceived risk of thromboembolic events after recovery from COVID-19. A significant proportion of patients reported persistent post-COVID-19 symptoms. Breathing difficulty was the most common symptom noted by us, closely followed by fatigue.

HOW TO CITE THIS ARTICLE

Rai DK, Sahay N. Six-month Morbidity and Mortality in Patients after Recovery from COVID-19. Indian J Crit Care Med 2022;26(11):1179-1183.

摘要

背景

本次电话调查旨在确定在一家三级新冠病毒疾病2019(COVID-19)治疗医院出院后6个月内,因任何原因死亡的COVID-19患者比例。我们还分析了是否有任何临床和/或实验室变量与出院后死亡率相关。

材料与方法

纳入2020年7月至2020年8月期间,因COVID-19首次住院后从一家三级COVID-19治疗医院出院的所有成年患者(年龄≥18岁)。出院6个月后进行电话访谈,以评估这些患者的发病率和死亡率。

结果

在457名有回应的患者中,79名患者(17.21%)有症状,其中呼吸急促是最常见的症状(6.12%)。研究患者中有(5.93%)出现疲劳,其次是咳嗽(4.59%)、睡眠障碍(4.37%)和头痛(2.62%)。在457名有回应的患者中,42名患者(9.19%)因其持续症状需要专家医疗咨询。36名患者(7.88%)在出院后6个月内因COVID-19后并发症需要再次住院。共有10名患者(2.18%)在出院后6个月内死亡。6名男性,4名女性。这些患者中的大多数(7/10)在出院后的第二个月死亡。7名患者患有中度至重度COVID-19疾病,其中大多数(7/10)未在重症监护病房(ICU)接受治疗。

结论

尽管从COVID-19康复后血栓栓塞事件的感知风险较高,但在我们的调查中,COVID-19后死亡率数字并不很高。相当一部分患者报告有持续的COVID-19后症状。呼吸困难是我们注意到的最常见症状,其次是疲劳。

如何引用本文

Rai DK,Sahay N。COVID-19康复后患者的6个月发病率和死亡率。《印度重症监护医学杂志》2022;26(11):1179 - 1183。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d2a/9983654/b6316dea7a8e/ijccm-26-1179-g001.jpg

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