Wasifuddin Mustafa, Ilerhunmwuwa Nosakhare, Uche Ifeanyi, Aiwuyo Henry O, Hakobyan Narek, Sedeta Ephrem, Perry Jamal C, Torere Beatrice E, Abowali Hesham Ali, Mararenko Larisa
Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.
Internal Medicine, North Mississippi Medical Center, Tupelo, USA.
Cureus. 2023 Jan 29;15(1):e34354. doi: 10.7759/cureus.34354. eCollection 2023 Jan.
Endometrial cancer is the most common cancer of the female genital tract. It can rarely metastasize to the pleura and present as a malignant pleural effusion. Here we present the case of a 61-year-old female with two primary malignancies, breast and endometrium, who presented to us with shortness of breath. Imaging was suggestive of a malignant pleural effusion. Diagnostic and therapeutic thoracentesis were performed that were initially suggestive of a breast source. However, final pleural fluid studies showed endometrial serous carcinoma as the source of the effusion. The patient received pembrolizumab and lenvatinib treatment and continues to be followed up in our clinic.
子宫内膜癌是女性生殖道最常见的癌症。它很少转移至胸膜并表现为恶性胸腔积液。在此，我们报告一例61岁女性病例，该患者患有两种原发性恶性肿瘤，即乳腺癌和子宫内膜癌，因气短前来就诊。影像学检查提示为恶性胸腔积液。进行了诊断性和治疗性胸腔穿刺术，最初提示积液来源为乳腺。然而，最终的胸腔积液检查显示积液来源为子宫内膜浆液性癌。该患者接受了帕博利珠单抗和乐伐替尼治疗，目前仍在我们诊所接受随访。
