Murugan Jagannaathan, Balasubramaniyan Jayanty Venkata, Mathiyalagan Praveen Kumar, Ramesh Yashwanth, Selvam Meera, Charley Chris, Muralidharan Harini, Venati Rishitha, Dhanasekaran Indrani Devi, Rajanandh Muhasarparur Ganesan
Department of Pharmacy Practice, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research Deemed to be University Porur, Chennai India.
Department of Cardiology Deemed to be University Porur, Chennai India.
Health Sci Rep. 2023 Mar 1;6(3):e1141. doi: 10.1002/hsr2.1141. eCollection 2023 Mar.
The prevalence of acute coronary syndrome (ACS) has been rising in the younger population worldwide. To fully comprehend the effects of the condition, it is crucial to examine the evolving characteristics and treatment options. The purpose of this study is to evaluate the characteristics and treatment analysis for young ACS patients in a tertiary care setting.
This cross-sectional, retrospective, single-center study included a random sample of patients who had been hospitalized for ACS over the period of a year. We collected and analyzed data on risk factors, diagnoses, angiographic patterns, and potential treatments.
The study involved 198 young ACS patients in total. The majority of patients (57%) had no risk factors, and the majority of them (44%) had ST-elevation myocardial infarction (STEMI) as their diagnosis. The most common type (48%) was single-vessel disease (SVD). Statins and antiplatelet medications made up the majority of the patients' nonsurgical treatments (88% and 87%, respectively). A statistically significant difference exists between young and older ACS patients with gender ( < 0.01). However, it is not clinically relevant.
Men were the majority of young ACS patients, and STEMI, SVD were more prevalent. The majority of young ACS patients had no significant risk factors. To determine the risk factors of young ACS patients, a more thorough case-control study is critically needed.
全球范围内，急性冠状动脉综合征（ACS）在年轻人群中的患病率一直在上升。为全面了解该疾病的影响，审视其不断演变的特征和治疗选择至关重要。本研究的目的是评估三级医疗环境中年轻ACS患者的特征及治疗分析。
这项横断面、回顾性、单中心研究纳入了在一年期间因ACS住院的患者随机样本。我们收集并分析了有关危险因素、诊断、血管造影模式和潜在治疗的数据。
该研究共纳入198例年轻ACS患者。大多数患者（57%）没有危险因素，其中大多数（44%）诊断为ST段抬高型心肌梗死（STEMI）。最常见的类型（48%）是单支血管病变（SVD）。他汀类药物和抗血小板药物构成了患者非手术治疗的大部分（分别为88%和87%）。年轻和老年ACS患者在性别方面存在统计学显著差异（<0.01）。然而，这在临床上并无相关性。
年轻ACS患者以男性居多，STEMI、SVD更为普遍。大多数年轻ACS患者没有显著的危险因素。为确定年轻ACS患者的危险因素，迫切需要进行更全面的病例对照研究。
