Villamaria Emma, Dacy Nicole, Preston Allie, Housewright Chad
McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
Department of Dermatology, Baylor Scott & White Medical Center - Temple and Texas A&M College of Medicine, Temple, Texas.
Proc (Bayl Univ Med Cent). 2023 Jan 17;36(2):249-250. doi: 10.1080/08998280.2023.2165296. eCollection 2023.
Topical 5-fluorouracil is a common treatment for actinic keratoses. Its side effects may include intense erythema, erosions, contact dermatitis, systemic intolerance in susceptible individuals, and ulcerations. We present a case of a 78-year-old woman who developed unilateral ectropion after topical 5-fluorouracil application. This case highlights the importance of clear patient instruction while prescribing topical 5-fluorouracil. Patients should be advised to wash their hands thoroughly after application. We also stress the importance of counseling patients to keep the medication away from the orbital rim, eye, and eyelid.
外用5-氟尿嘧啶是治疗光化性角化病的常用方法。其副作用可能包括强烈的红斑、糜烂、接触性皮炎、易感个体的全身不耐受以及溃疡。我们报告一例78岁女性在外用5-氟尿嘧啶后出现单侧睑外翻的病例。该病例强调了在开具外用5-氟尿嘧啶处方时对患者进行明确指导的重要性。应建议患者在用药后彻底洗手。我们还强调了告知患者将药物远离眼眶边缘、眼睛和眼睑的重要性。
