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Benefits of Bempedoic Acid - Clearer Now.

作者信息

Alexander John H

机构信息

From the Division of Cardiology, Duke Clinical Research Institute, Duke Health, Durham, NC.

出版信息

N Engl J Med. 2023 Apr 13;388(15):1425-1426. doi: 10.1056/NEJMe2301490. Epub 2023 Mar 4.

DOI:10.1056/NEJMe2301490
PMID:36876748
Abstract
摘要

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N Engl J Med. 2023 Apr 13;388(15):1425-1426. doi: 10.1056/NEJMe2301490. Epub 2023 Mar 4.
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Efficacy and safety of bempedoic acid added to ezetimibe in statin-intolerant patients with hypercholesterolemia: A randomized, placebo-controlled study.在不能耐受他汀类药物的高胆固醇血症患者中,添加苯扎贝特酸与依折麦布联合治疗的疗效和安全性:一项随机、安慰剂对照研究。
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A Meta-Analysis of Cardiovascular Outcomes in Patients With Hypercholesterolemia Treated With Bempedoic Acid.贝派地酸治疗高胆固醇血症患者心血管结局的荟萃分析。
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J Cardiovasc Med (Hagerstown). 2021 Mar 1;22(3):162-171. doi: 10.2459/JCM.0000000000001108.

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Efficacy and Safety of Bempedoic Acid in Patients with High Cardiovascular Risk: An Update.贝匹地酸在高心血管风险患者中的疗效和安全性:一项更新。
Curr Vasc Pharmacol. 2024;22(4):242-250. doi: 10.2174/0115701611290763240126045433.
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Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials.
贝匹地酸的安全性和疗效:随机对照试验的系统评价和荟萃分析。
Cardiovasc Diabetol. 2023 Nov 28;22(1):324. doi: 10.1186/s12933-023-02022-z.
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Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice.ACLY 抑制剂与 GLP-1R 激动剂联合应用可对小鼠非酒精性脂肪性肝炎和肝纤维化产生附加益处。
Cell Rep Med. 2023 Sep 19;4(9):101193. doi: 10.1016/j.xcrm.2023.101193.
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Bempedoic Acid can Reduce Cardiovascular Events in Combination with Statins or As Monotherapy: A Systematic Review and Meta-analysis.贝匹地酸联合他汀类药物或单药治疗可降低心血管事件风险:系统评价和荟萃分析。
Am J Cardiovasc Drugs. 2023 Nov;23(6):695-708. doi: 10.1007/s40256-023-00606-4. Epub 2023 Sep 6.
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J Clin Med. 2023 May 24;12(11):3652. doi: 10.3390/jcm12113652.