Kosten T R, Rounsaville B J, Kleber H D
Substance Abuse Treatment Unit, APT Foundation, New Haven, Connecticut 06511.
Am J Drug Alcohol Abuse. 1987;13(1-2):19-32. doi: 10.3109/00952998709001498.
A recent 6-month follow-up of methadone maintenance (MM) suggested that addicts supported by public assistance before seeking MM have a globally poor prognosis compared to addicts supported by employment or illegal activities. We therefore examined 2.5-year outcome among addicts prognostically stratified by three major sources of pretreatment income: employment (n = 48), welfare (n = 46), and criminal activities (n = 57). Significant improvements in substance abuse, family, legal, and psychological problems were reported by all three groups. Furthermore, the welfare group showed the most improvement in medical status and on the Social Adjustment, Maudsley neuroticism, and Beck Depression scales. Thus, the welfare patients did not appear to have a globally poorer prognosis, although they showed the least improvement in employment and legal problems. To examine whether welfare patients on MM had no more than "expected" improvement in legal and employment problems, patients treated with MM (n = 83) were compared to those getting only detoxification (DT) (n = 40). Welfare patients showed no more improvement in these two areas from MM treatment than from DT alone, while at follow-up the "employed" and "criminal" groups had substantially less illegal income and unemployment with MM than with DT alone. Thus, welfare patients may do relatively poorly in some areas when treated on MM.
美沙酮维持治疗(MM)最近一项为期6个月的随访表明,与那些靠就业或从事非法活动维持生计的成瘾者相比,在寻求美沙酮维持治疗前依靠公共援助维持生计的成瘾者总体预后较差。因此,我们对根据治疗前收入的三个主要来源进行预后分层的成瘾者进行了为期2.5年的随访研究,这三个来源分别是:就业(n = 48)、福利(n = 46)和犯罪活动(n = 57)。所有三组成瘾者在药物滥用、家庭、法律和心理问题方面均有显著改善。此外,福利组在健康状况以及社会适应、莫兹利神经质和贝克抑郁量表方面的改善最为明显。因此,尽管福利组成瘾者在就业和法律问题方面的改善最少,但他们的总体预后似乎并不差。为了研究接受美沙酮维持治疗的福利组成瘾者在法律和就业问题上的改善是否未超过“预期”,我们将接受美沙酮维持治疗的患者(n = 83)与仅接受脱毒治疗(DT)的患者(n = 40)进行了比较。福利组成瘾者在这两个方面,美沙酮维持治疗组的改善并不比单纯脱毒治疗组更多,而在随访时,“就业”组和“犯罪”组成瘾者在接受美沙酮维持治疗时的非法收入和失业率相比单纯接受脱毒治疗时大幅降低。因此,接受美沙酮维持治疗的福利组成瘾者在某些方面可能相对较差。