Water Source Exploration Team, Guizhou Bureau of Coal Geological Exploration, Guiyang, 550000, China.
Guizhou Coal Mine Geological Engineering Consultant and Geological Environmental Monitoring Center, Guiyang, 550000, China.
Environ Sci Pollut Res Int. 2023 Apr;30(17):48778-48792. doi: 10.1007/s11356-023-26263-3. Epub 2023 Mar 7.
Quinolone (QN) antibiotics are a kind of broad-spectrum antibiotics commonly used in the treatment of human and animal diseases. They have the characteristics of strong antibacterial activity, stable metabolism, low production cost, and no cross-resistance with other antibacterial drugs. They are widely used in the world. QN antibiotics cannot be completely digested and absorbed in organisms and are often excreted in urine and feces in the form of original drugs or metabolites, which are widely occurring in surface water, groundwater, aquaculture wastewater, sewage treatment plants, sediments, and soil environment, thus causing environmental pollution. In this paper, the pollution status, biological toxicity, and removal methods of QN antibiotics at home and abroad were reviewed. Literature data showed that QNs and its metabolites had serious ecotoxicity. Meanwhile, the spread of drug resistance induced by continuous emission of QNs should not be ignored. In addition, adsorption, chemical oxidation, photocatalysis, and microbial removal of QNs are often affected by a variety of experimental conditions, and the removal is not complete, so it is necessary to combine a variety of processes to efficiently remove QNs in the future.
喹诺酮（QN）类抗生素是一种广泛应用于人类和动物疾病治疗的广谱抗生素。它们具有抗菌活性强、代谢稳定、生产成本低、与其他抗菌药物无交叉耐药性等特点，在世界范围内得到广泛应用。QN 类抗生素在生物体中不能被完全消化和吸收，通常以原药或代谢物的形式随尿液和粪便排出，广泛存在于地表水、地下水、水产养殖废水中、污水处理厂、沉积物和土壤环境中，从而造成环境污染。本文综述了国内外 QN 类抗生素的污染状况、生物毒性及其去除方法。文献资料表明，QNs 及其代谢物具有严重的生态毒性。同时，QNs 的持续排放引起的耐药性传播也不容忽视。此外，QNs 的吸附、化学氧化、光催化和微生物去除往往受到多种实验条件的影响，去除不彻底，因此未来有必要结合多种工艺来高效去除 QNs。
