Özlü Aysun, Akdeniz Leblebicier Merve
Department of Physical Medicine and Rehabilitation, Kütahya Health Sciences University, Kütahya, Türkiye.
Arch Rheumatol. 2022 Oct 19;37(4):603-612. doi: 10.46497/ArchRheumatol.2022.9552. eCollection 2022 Dec.
This study aimed to compare kinesiophobia, fatigue, physical activity, and quality of life (QoL) between the patients with rheumatoid arthritis (RA) in remission and a healthy population.
The prospective controlled study included 45 female patients (mean age: 54.22±8.2 year; range, 37 to 67 year) with a diagnosis of RA determined to be in remission according to the Disease Activity Score in 28 Joints (DAS28) being ≤2.6 between January 2022 and February 2022. As a control group, 45 female healthy volunteers (mean age: 52.2±8.2 year; range, 34 to 70 year) of similar age were evaluated. The QoL, disease activity, pain, kinesiophobia, fatigue severity, and physical activity were assessed using the Health Assessment Questionnaire, DAS28, Visual Analog Scale, Tampa Scale of Kinesiophobia, Fatigue Severity Scale, and International Physical Activity Questionnaire, respectively.
There was no significant difference between the groups in demographic data. A statistically significant difference was found between the groups in terms of pain, C-reactive protein level, fatigue, kinesiophobia, QoL, and total, high, and moderate physical activity scores (p<0.001). Among the RA patients in remission, there was a significant correlation between kinesiophobia and moderate physical activity and QoL, as well as between fatigue and high physical activity (p<0.05).
Patient education and multidisciplinary approach strategies should be developed to increase the QoL and physical activity and reduce kinesiophobia in RA patients in remission since there may be a decrease in physical activity due to kinesiophobia, fatigue, and fear of movement in this patient group compared to the healthy population, impairing their QoL.
本研究旨在比较缓解期类风湿关节炎（RA）患者与健康人群之间的运动恐惧、疲劳、身体活动及生活质量（QoL）。
这项前瞻性对照研究纳入了45例女性患者（平均年龄：54.22±8.2岁；范围37至67岁），她们于2022年1月至2022年2月期间被诊断为RA，根据28个关节疾病活动评分（DAS28）判定处于缓解期，DAS28≤2.6。作为对照组，评估了45例年龄相仿的女性健康志愿者（平均年龄：52.2±8.2岁；范围34至70岁）。分别使用健康评估问卷、DAS28、视觉模拟量表、坦帕运动恐惧量表、疲劳严重程度量表及国际身体活动问卷对生活质量、疾病活动度、疼痛、运动恐惧、疲劳严重程度及身体活动进行评估。
两组的人口统计学数据无显著差异。两组在疼痛、C反应蛋白水平、疲劳、运动恐惧、生活质量以及总身体活动、高强度身体活动和中等强度身体活动得分方面存在统计学显著差异（p<0.001）。在缓解期RA患者中，运动恐惧与中等强度身体活动及生活质量之间，以及疲劳与高强度身体活动之间存在显著相关性（p<0.05）。
应制定患者教育和多学科方法策略，以提高缓解期RA患者的生活质量和身体活动水平，并减少运动恐惧，因为与健康人群相比，该患者群体可能因运动恐惧、疲劳和对运动的恐惧而导致身体活动减少，从而损害其生活质量。
