A new path to alternative lengthening of telomeres?
作者信息
Becher Oren J
机构信息
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
出版信息
Neuro Oncol. 2023 Jul 6;25(7):1343-1344. doi: 10.1093/neuonc/noad054.
Abstract
摘要
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Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants.
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