Department of Anaesthesiology, Chettinad Hospital and Research Institute, Tamil Nadu, India.
Ethiop J Health Sci. 2023 Jan;33(1):107-114. doi: 10.4314/ejhs.v33i1.14.
We aimed to compare serum lactate levels of multi-drug poisoned patients to determine whether knowing the level may help emergency clinicians in predicting the patients' prognoses.
The patients were divided into two groups according to the number of kinds of drugs taken (Group 1: patients took 2 kinds of drugs; Group 2: patients took 3 or more kinds of drugs). The groups' initial venous lactate levels, lactate levels before discharge, lengths of stay in the emergency department, hospitalisation units, clinics, and outcomes were recorded on the study form. These findings of the patient groups were then compared.
When we evaluated the first lactate levels and lengths of stay in the emergency department, we found that 72% of the patients with initial lactate levels ≥13.5 mg/dL stayed more than 12 hours in the emergency department. Twenty-five (30.86%) patients in the second group stayed ≥12 hours in the emergency department, and their mean initial serum lactate level was significantly related (p=0.02, AUC=071). The mean initial serum lactate levels of both groups were positively related with their lengths of stay in the emergency department. The mean initial lactate levels of patients who stayed ≥12 hours and those who stayed <12 hours in the second group were statistically significant, and the mean lactate level of the patients who stayed ≥12 hours in the second group was lower.
Serum lactate levels may be helpful in determining a patient's length of stay in the emergency department in the case of multi-drug poisoning.
我们旨在比较多药中毒患者的血清乳酸水平，以确定了解该水平是否有助于急诊临床医生预测患者的预后。
根据服用的药物种类（第 1 组：患者服用 2 种药物；第 2 组：患者服用 3 种或更多种药物）将患者分为两组。记录两组患者的初始静脉乳酸水平、出院前的乳酸水平、在急诊科的停留时间、住院时间、门诊时间和结局。然后比较患者组的这些发现。
当我们评估首次乳酸水平和在急诊科的停留时间时，我们发现初始乳酸水平≥13.5mg/dL 的 72%患者在急诊科停留时间超过 12 小时。第二组中有 25 名（30.86%）患者在急诊科停留时间超过 12 小时，他们的初始血清乳酸水平明显相关（p=0.02，AUC=0.71）。两组的初始血清乳酸水平与在急诊科的停留时间呈正相关。第二组中在急诊科停留≥12 小时和停留<12 小时的患者的平均初始乳酸水平有统计学意义，且第二组中在急诊科停留≥12 小时的患者的乳酸水平较低。
血清乳酸水平可能有助于确定多药中毒患者在急诊科的停留时间。
