Parammal Alikutty Jamsheer, Raj Anoop, Soofi Sirajudheen K, Alkhateeb Amer A, Soliman Ahmed A, Al Amiri Fawwaz R, Abujaber Ahmad A, Peediyakkal Mohamed Zuhail K, Khatib Mohamad, Nashwan Abdulqadir J
Critical Care Medicine, Hamad Medical Corporation, Doha, QAT.
Nursing, Hamad Medical Corporation, Doha, QAT.
Cureus. 2023 Feb 4;15(2):e34625. doi: 10.7759/cureus.34625. eCollection 2023 Feb.
Acute kidney injury (AKI) is a serious medical condition that can have many causes, including rhabdomyolysis. Rhabdomyolysis is the breakdown of muscle tissue that can lead to the release of muscle fiber contents into the bloodstream. This can cause serious damage to the kidneys, leading to AKI. In this case, a young bodybuilder was diagnosed with rhabdomyolysis induced by AKI after consuming Ibuprofen for a casual fever. The etiology of AKI in rhabdomyolysis is complex, with multiple factors contributing to the development of the condition. These include muscle trauma, dehydration, infection, and drug toxicity. In this case, Ibuprofen may have contributed to the development of AKI, as it can cause kidney damage when taken in large doses. Additionally, the bodybuilder's physical activity may have contributed to the development of rhabdomyolysis, as intense exercise can cause muscle damage. Treatment for AKI in rhabdomyolysis patients typically involves aggressive fluid resuscitation, electrolyte replacement, and dialysis if necessary. Additionally, the underlying cause of the rhabdomyolysis must be identified and treated. In this case, the patient should be monitored closely for any signs of kidney damage, and the Ibuprofen should be discontinued. In conclusion, this is a case of a relatively common presentation with uncommon circumstances. It is crucial to have a heightened understanding of the likelihood of AKI in patients with rhabdomyolysis and the impact of drug toxicity in exacerbating the condition. Early diagnosis and treatment are essential for the successful management of AKI.
急性肾损伤（AKI）是一种严重的病症，可能有多种病因，包括横纹肌溶解症。横纹肌溶解症是肌肉组织的分解，可导致肌肉纤维成分释放到血液中。这会对肾脏造成严重损害，导致急性肾损伤。在本病例中，一名年轻的健美运动员因偶尔发烧服用布洛芬后被诊断为急性肾损伤诱发的横纹肌溶解症。横纹肌溶解症中急性肾损伤的病因复杂，多种因素促成了该病症的发展。这些因素包括肌肉创伤、脱水、感染和药物毒性。在本病例中，布洛芬可能促成了急性肾损伤的发展，因为大剂量服用时它会导致肾损伤。此外，健美运动员的体育活动可能促成了横纹肌溶解症的发展，因为剧烈运动可导致肌肉损伤。横纹肌溶解症患者急性肾损伤的治疗通常包括积极的液体复苏、电解质补充，必要时进行透析。此外，必须识别并治疗横纹肌溶解症的潜在病因。在本病例中，应密切监测患者是否有肾损伤的任何迹象，并停用布洛芬。总之，这是一个具有不寻常情况的相对常见表现的病例。提高对横纹肌溶解症患者发生急性肾损伤可能性以及药物毒性在加重病情方面影响的认识至关重要。早期诊断和治疗对于成功管理急性肾损伤至关重要。
