• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年心力衰竭患者的多重用药:老年医学专家和药剂师的作用

Polypharmacy in Older People With Heart Failure: Roles of the Geriatrician and Pharmacist.

作者信息

Stefil Maria, Dixon Matthew, Bahar Jameela, Saied Schabnam, Mashida Knievel, Heron Olivia, Shantsila Eduard, Walker Lauren, Akpan Asangaedem, Lip Gregory Yh, Sankaranarayanan Rajiv

机构信息

Liverpool Centre for Cardiovascular Science, University of Liverpool Liverpool, UK.

Department of Cardiology, Liverpool University Hospitals NHS Foundation Trust Liverpool, UK.

出版信息

Card Fail Rev. 2022 Dec 19;8:e34. doi: 10.15420/cfr.2022.14. eCollection 2022 Jan.

DOI:10.15420/cfr.2022.14
PMID:36891063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9987511/
Abstract

Heart failure (HF) is a common health condition that typically affects older adults. Many people with HF are cared for on an inpatient basis, by noncardiologists, such as acute medical physicians, geriatricians and other physicians. Treatment options for HF are ever increasing, and adherence to guidelines for prognostic therapy contributes to polypharmacy, which is very familiar to clinicians who care for older people. This article explores the recent trials in both HF with reduced ejection fraction and HF with preserved ejection fraction and the limitations of international guidance in their management with respect to older people. In addition, this article discusses the challenge of managing polypharmacy in those with advanced age, and the importance of involving a geriatrician and pharmacist in the HF multidisciplinary team to provide a holistic and person-centred approach to optimisation of HF therapies.

摘要

心力衰竭(HF)是一种常见的健康状况,通常影响老年人。许多心力衰竭患者由非心脏病专家在住院基础上进行护理,如急性内科医生、老年病医生和其他医生。心力衰竭的治疗选择不断增加,遵循预后治疗指南会导致多重用药,这对于照顾老年人的临床医生来说非常熟悉。本文探讨了近期射血分数降低的心力衰竭和射血分数保留的心力衰竭试验,以及国际指南在老年人管理方面的局限性。此外,本文还讨论了管理高龄患者多重用药的挑战,以及在心力衰竭多学科团队中纳入老年病医生和药剂师以提供全面和以患者为中心的方法来优化心力衰竭治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b05/9987511/d565f6d7911a/cfr-08-e34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b05/9987511/d565f6d7911a/cfr-08-e34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b05/9987511/d565f6d7911a/cfr-08-e34-g001.jpg

相似文献

1
Polypharmacy in Older People With Heart Failure: Roles of the Geriatrician and Pharmacist.老年心力衰竭患者的多重用药:老年医学专家和药剂师的作用
Card Fail Rev. 2022 Dec 19;8:e34. doi: 10.15420/cfr.2022.14. eCollection 2022 Jan.
2
The management of diagnosed heart failure in older people in primary care.基层医疗中老年人心力衰竭的诊治管理。
Maturitas. 2017 Dec;106:26-30. doi: 10.1016/j.maturitas.2017.08.011. Epub 2017 Aug 25.
3
Polypharmacy in Older Heart Failure Patients: a Multidisciplinary Approach.老年心力衰竭患者的多种药物治疗:多学科方法。
Curr Heart Fail Rep. 2022 Oct;19(5):290-302. doi: 10.1007/s11897-022-00559-w. Epub 2022 Jun 20.
4
Implementation and evaluation of specialist heart failure pharmacist prescribing clinics.专科心力衰竭药剂师开方诊所的实施与评估
Int J Clin Pharm. 2025 Feb;47(1):8-14. doi: 10.1007/s11096-024-01808-9. Epub 2024 Oct 5.
5
Multispecialty multidisciplinary input into comorbidities along with treatment optimisation in heart failure reduces hospitalisation and clinic attendance.多学科多专业共同参与心力衰竭的合并症治疗并优化治疗方案可减少住院和就诊次数。
Open Heart. 2022 Jul;9(2). doi: 10.1136/openhrt-2022-001979.
6
7
Effect of Clinical Geriatric Assessments and Collaborative Medication Reviews by Geriatrician and Family Physician for Improving Health-Related Quality of Life in Home-Dwelling Older Patients Receiving Polypharmacy: A Cluster Randomized Clinical Trial.临床老年评估和老年病医生与家庭医生协作进行药物审查对改善接受多种药物治疗的居家老年患者健康相关生活质量的效果:一项整群随机临床试验。
JAMA Intern Med. 2020 Feb 1;180(2):181-189. doi: 10.1001/jamainternmed.2019.5096.
8
Establishing a proactive geriatrician led comprehensive geriatric assessment in older emergency surgery patients: Outcomes of a pilot study.在老年急诊手术患者中建立由老年病医生主导的主动式综合老年评估:一项试点研究的结果
Int J Clin Pract. 2018 May;72(5):e13096. doi: 10.1111/ijcp.13096. Epub 2018 Apr 23.
9
Definition of Polypharmacy in Heart Failure: A Scoping Review of the Literature.心力衰竭中多重用药的定义:文献综述
Cardiol Res. 2024 Apr;15(2):75-85. doi: 10.14740/cr1636. Epub 2024 Apr 15.
10
Evidence-based Therapy in Older Patients with Heart Failure with Reduced Ejection Fraction.射血分数降低的老年心力衰竭患者的循证治疗
Card Fail Rev. 2022 Apr 28;8:e16. doi: 10.15420/cfr.2021.34. eCollection 2022 Jan.

引用本文的文献

1
Contextual Factors Affecting Adherence Revealed by Old Patients with Heart Failure in Hospital and Primary Care Interactions: A Descriptive Study.住院及基层医疗互动中影响老年心力衰竭患者依从性的情境因素:一项描述性研究
Patient Prefer Adherence. 2025 Apr 14;19:1075-1087. doi: 10.2147/PPA.S505297. eCollection 2025.
2
How to handle polypharmacy in heart failure. A clinical consensus statement of the Heart Failure Association of the ESC.如何处理心力衰竭中的多重用药问题。欧洲心脏病学会心力衰竭协会的临床共识声明。
Eur J Heart Fail. 2025 May;27(5):747-759. doi: 10.1002/ejhf.3642. Epub 2025 Mar 17.
3
An Observational Study of Evidence-Based Therapies in Older Patients with Heart Failure with Reduced Ejection Fraction: Insights from a Dedicated Heart Failure Clinic.

本文引用的文献

1
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). With the special contribution of the Heart Failure Association (HFA) of the ESC.2021 ESC 急性和慢性心力衰竭诊断和治疗指南:由欧洲心脏病学会(ESC)急性和慢性心力衰竭诊断和治疗工作组制定。特别感谢欧洲心脏病学会心力衰竭协会(HFA)的贡献。
Eur J Heart Fail. 2022 Jan;24(1):4-131. doi: 10.1002/ejhf.2333.
2
Polypharmacy and Clinical Outcomes in Hospitalized Patients With Acute Decompensated Heart Failure.住院的急性失代偿性心力衰竭患者的药物治疗和临床结局。
J Cardiovasc Nurs. 2023;38(1):33-43. doi: 10.1097/JCN.0000000000000885. Epub 2022 Jan 14.
3
射血分数降低的老年心力衰竭患者循证治疗的观察性研究:来自专业心力衰竭诊所的见解
J Clin Med. 2024 Nov 26;13(23):7171. doi: 10.3390/jcm13237171.
4
Multitarget Pharmacology of Sulfur-Nitrogen Heterocycles: Anticancer and Antioxidant Perspectives.硫氮杂环化合物的多靶点药理学:抗癌与抗氧化视角
Antioxidants (Basel). 2024 Jul 25;13(8):898. doi: 10.3390/antiox13080898.
5
Definition of Polypharmacy in Heart Failure: A Scoping Review of the Literature.心力衰竭中多重用药的定义:文献综述
Cardiol Res. 2024 Apr;15(2):75-85. doi: 10.14740/cr1636. Epub 2024 Apr 15.
6
What is the association of polypharmacy with frailty in heart failure? A systematic review and meta-analysis.多重用药与心力衰竭患者衰弱之间有何关联?一项系统评价与荟萃分析。
J Frailty Sarcopenia Falls. 2024 Mar 1;9(1):51-65. doi: 10.22540/JFSF-09-051. eCollection 2024 Mar.
Polypharmacy Management in the Older Adults: A Scoping Review of Available Interventions.老年人的多重用药管理:现有干预措施的范围综述
Front Pharmacol. 2021 Nov 26;12:734045. doi: 10.3389/fphar.2021.734045. eCollection 2021.
4
Empagliflozin in Heart Failure with a Preserved Ejection Fraction.恩格列净治疗射血分数保留的心力衰竭。
N Engl J Med. 2021 Oct 14;385(16):1451-1461. doi: 10.1056/NEJMoa2107038. Epub 2021 Aug 27.
5
Polypharmacy definition and prevalence in heart failure: a systematic review.心力衰竭中药物滥用的定义和流行率:系统评价。
Heart Fail Rev. 2022 Mar;27(2):465-492. doi: 10.1007/s10741-021-10135-4. Epub 2021 Jul 2.
6
Attitudes toward deprescribing among adults with heart failure with preserved ejection fraction.射血分数保留的心力衰竭成人对药物减量的态度。
J Am Geriatr Soc. 2021 Jul;69(7):1948-1955. doi: 10.1111/jgs.17204. Epub 2021 May 12.
7
2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee.《2017年美国心脏病学会(ACC)心力衰竭治疗优化专家共识决策路径2021年更新:关于射血分数降低的心力衰竭的10个关键问题解答:美国心脏病学会解决方案集监督委员会报告》
J Am Coll Cardiol. 2021 Feb 16;77(6):772-810. doi: 10.1016/j.jacc.2020.11.022. Epub 2021 Jan 11.
8
Influence of polypharmacy on patients with heart failure with preserved ejection fraction: a retrospective analysis on adverse outcomes in the TOPCAT trial.多药治疗对射血分数保留的心力衰竭患者的影响:TOPCAT 试验中不良结局的回顾性分析。
Br J Gen Pract. 2020 Dec 28;71(702):e62-e70. doi: 10.3399/bjgp21X714245. Print 2021 Jan.
9
Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.索格列净治疗伴有近期恶化心力衰竭的糖尿病患者。
N Engl J Med. 2021 Jan 14;384(2):117-128. doi: 10.1056/NEJMoa2030183. Epub 2020 Nov 16.
10
Polypharmacy and emergency readmission to hospital after critical illness: a population-level cohort study.危重病后多药治疗与急诊再次入院:基于人群队列的研究。
Br J Anaesth. 2021 Feb;126(2):415-422. doi: 10.1016/j.bja.2020.09.035. Epub 2020 Oct 31.