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[肠道真菌在慢性肝病中的作用特点及研究进展]

[Characteristics and research progress on the role of intestinal fungi in chronic liver disease].

作者信息

Zhang L L, Deng W H, Wang W X

机构信息

Department of General Surgery, Renmin Hospital of Whuhan University, Whuhan 430071, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2022 Nov 20;30(11):1285-1288. doi: 10.3760/cma.j.cn501113-20201030-00588.

Abstract

At present, a large number of studies have revealed that intestinal bacteria play a very complex role in benign liver diseases, while there is relatively little research on intestinal fungi. As part of the gut microbiome, intestinal fungi are insignificant in numbers compared with intestinal bacteria, but the impact of intestinal fungi on human health and diseases cannot be ignored. This paper summarizes the characteristics and research progress of intestinal fungi in patients with alcoholic liver disease, nonalcoholic fatty liver disease, viral hepatitis and liver cirrhosis, so as to provide basis of reference and ideas for the further research on the diagnosis and treatment of intestinal fungi in benign liver diseases.

摘要

目前,大量研究表明肠道细菌在良性肝病中发挥着非常复杂的作用,而关于肠道真菌的研究相对较少。作为肠道微生物群的一部分,与肠道细菌相比,肠道真菌数量较少,但肠道真菌对人类健康和疾病的影响不容忽视。本文综述了酒精性肝病、非酒精性脂肪性肝病、病毒性肝炎和肝硬化患者肠道真菌的特点及研究进展,以期为良性肝病肠道真菌诊断与治疗的进一步研究提供参考依据和思路。

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