Department of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, India.
Endocr Metab Immune Disord Drug Targets. 2023;23(12):1491-1504. doi: 10.2174/1871530323666230309144825.
Metabolic syndrome, also referred to as Syndrome X or obesity syndrome is a cluster of diseases prevalent worldwide in both developed and developing countries. According to WHO, it is referred to as a pathological condition wherein multiple disorders are manifested in the same individual. These include hypertension, hyperglycemia, dyslipidemia and abdominal obesity.
Metabolic syndrome is one of the most serious non-communicable health hazards that have gained pivotal importance in the present scenario. The increasing prevalence affecting around 25 % of the world populace, mainly attributes to the acceptance of western culture, i.e. the intake of highcalorie food along with a substantial decrease in manual labor and adoption of sedentary lifestyles. Therefore, its timely prevention and management are the dire need in the present scenario.
For successful accomplishment of the present review, an exhaustive analysis was performed utilizing a pool of previous related literature. The terms used during the search included 'metabolic syndrome, prevalence, etiology, current pharmacotherapy for metabolic syndrome, etc. PUBMED, Medline and SCOPUS were explored for the study of abstracts, research and review papers in the quest for related data. The articles were downloaded and utilized for a meta-analysis study approach.
In this review, an attempt was made to apprehend and summarize the epidemiology and treatment strategies for metabolic syndrome with a better understanding of its pathogenesis. It was postulated that an early diagnostic approach and subsequent line of treatment is required to prevent the deterioration of an individual's health and life.
代谢综合征，也被称为综合征 X 或肥胖综合征，是一种在发达国家和发展中国家都普遍存在的疾病群。根据世界卫生组织的定义，它是指一种病理状态，其中同一个体表现出多种紊乱。这些紊乱包括高血压、高血糖、血脂异常和腹部肥胖。
代谢综合征是目前最重要的非传染性健康危害之一。它的患病率不断上升，影响着全球约 25%的人口，主要归因于对西方文化的接受，即摄入高热量食物，同时大量减少体力劳动和采用久坐的生活方式。因此，在当前情况下，及时预防和管理代谢综合征至关重要。
为了成功完成本次综述，我们进行了全面的分析，利用了大量以前相关的文献。在搜索过程中使用的术语包括“代谢综合征、流行率、病因、代谢综合征的当前药物治疗等”。我们在 PUBMED、Medline 和 SCOPUS 上搜索了摘要、研究和综述论文，以寻找相关数据。下载并利用这些文章进行了荟萃分析研究。
在本次综述中，我们试图理解和总结代谢综合征的流行病学和治疗策略，以更好地了解其发病机制。我们提出，需要早期诊断方法和随后的治疗方案，以防止个体健康和生命的恶化。
