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简短的术前情绪压力筛查可预测术后阿片类药物的使用:一项观察性研究。

The brief measure of preoperative emotional stress screens preoperative maladaptive psychological features and predicts postoperative opioid use: an observational study.

机构信息

Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Programa de Pós-Graduação em Epidemiologia, Porto Alegre, RS, Brazil; Hospital das Clínicas de Porto Alegre, Unidade de Bioestatística, Diretoria de Pesquisa, Porto Alegre, RS, Brazil.

Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Departamento de Cirurgia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Médicas, Porto Alegre, RS, Brazil; Hospital das Clínicas de Porto Alegre, Laboratório de Dor e Neuromodulação, Porto Alegre, RS, Brazil.

出版信息

Braz J Anesthesiol. 2024 Mar-Apr;74(2):744425. doi: 10.1016/j.bjane.2023.02.004. Epub 2023 Mar 8.

Abstract

BACKGROUND

The Brief Measure of Preoperative Emotional Stress (B-MEPS) is a suitable screening tool for Preoperative Emotional Stress (PES). However, personalized decision-making demands practical interpretation of the refined version of B-MEPS. Thus, we propose and validate cut-off points on the B-MEPS to classify PES. Also, we assessed if the cut-off points screened preoperative maladaptive psychological features and predicted postoperative opioid use.

METHODS

This observational study comprises samples of two other primary studies, with 1009 and 233 individuals, respectively. The latent class analysis derived emotional stress subgroups using B-MEPS items. We compared membership with the B-MEPS score through the Youden index. Concurrent criterion validity of the cut-off points was performed with the severity of preoperative depressive symptoms, pain catastrophizing, central sensitization, and sleep quality. Predictive criterion validity was performed with opioid use after surgery.

RESULTS

We chose a model with three classes labeled mild, moderate, and severe. The Youden index points -0.1663 and 0.7614 of the B-MEPS score classify individuals, in the severe class, with a sensitivity of 85.7% (80.1%-90.3%) and specificity of 93.5% (91.5-95.1%). The cut-off points of the B-MEPS score have satisfactory concurrent and predictive criterion validity.

CONCLUSIONS

These findings showed that the preoperative emotional stress index on the B-MEPS offers suitable sensitivity and specificity for discriminating the severity of preoperative psychological stress. They provide a simple tool to identify patients prone to severe PES related to maladaptive psychological features, which might influence the perception of pain and analgesic opioid use in the postoperative period.

摘要

背景

术前情绪应激简易量表(B-MEPS)是一种适合于术前情绪应激(PES)的筛查工具。然而,个性化决策需要对 B-MEPS 的精细化版本进行实际解读。因此,我们提出并验证了 B-MEPS 的切点,以对 PES 进行分类。此外,我们评估了这些切点是否筛查出术前适应性不良的心理特征,并预测术后阿片类药物的使用。

方法

本观察性研究包含另外两项主要研究的样本,分别为 1009 人和 233 人。使用 B-MEPS 项目进行潜在类别分析,得出情绪应激亚组。通过约登指数比较成员身份与 B-MEPS 评分的关系。切点的同时效标准效度通过术前抑郁症状严重程度、疼痛灾难化、中枢敏化和睡眠质量进行评估。预测效标准效度通过手术后阿片类药物的使用进行评估。

结果

我们选择了一个具有三个类别的模型,分别标记为轻度、中度和重度。B-MEPS 评分的约登指数点 -0.1663 和 0.7614 将个体分为严重类,敏感性为 85.7%(80.1%-90.3%),特异性为 93.5%(91.5%-95.1%)。B-MEPS 评分的切点具有较好的同时效和预测效标准效度。

结论

这些发现表明,B-MEPS 上的术前情绪应激指数能够很好地区分术前心理应激的严重程度,具有较好的敏感性和特异性。它们提供了一种简单的工具,可以识别出容易出现与适应性不良心理特征相关的严重 PES 的患者,这可能会影响术后疼痛的感知和阿片类药物的使用。

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