Petrakis Nikki, Addison Mel, Penak Bianca, Schrader Silja, Mallard John, Clothier Hazel J, Buttery Jim P, Crawford Nigel W, Cheng Daryl R
SAEFVIC, Infection and Immunity, Murdoch Children's Research Institute, Murdoch Children's Research Institute, Parkville, Australia.
The Royal Children's Hospital Melbourne, Parkville, Australia.
Expert Rev Vaccines. 2023 Jan-Dec;22(1):299-306. doi: 10.1080/14760584.2023.2189463.
Shoulder Injury Related to Vaccine Administration (SIRVA) is a preventable adverse event following incorrect vaccine administration, which can result in significant long-term morbidity. There has been a notable surge in reported cases of SIRVA as a rapid national population-based COVID-19 immunization program has been rolled out across Australia.
Surveillance of Adverse Events Following Vaccination in the Community (SAEFVIC) in Victoria identified 221 suspected cases of SIRVA following the commencement of the COVID-19 vaccination program, reported between February 2021 and February 2022. This review describes the clinical features and outcomes of SIRVA in this population. Additionally, a suggested diagnostic algorithm is proposed, in order to facilitate early recognition and management of SIRVA.
151 cases were confirmed as SIRVA, with 49.0% having received vaccines at state vaccination centers. 75.5% were suspected incorrect administration site, with most patients experiencing shoulder pain and restricted movement within 24 hours of vaccination, lasting on average 3 months.
Improved awareness and education regarding SIRVA is imperative in a pandemic vaccine roll-out. The development of a structured framework for evaluating and managing suspected SIRVA will aid in timely diagnosis and treatment, essential to mitigate potential long-term complications.
疫苗接种相关肩部损伤(SIRVA)是疫苗接种不当后可预防的不良事件,可导致严重的长期发病率。随着澳大利亚全国范围内迅速开展基于人群的COVID-19免疫计划,SIRVA报告病例显著增加。
维多利亚州社区疫苗接种后不良事件监测(SAEFVIC)确定了2021年2月至2022年2月期间报告的221例COVID-19疫苗接种计划开始后的疑似SIRVA病例。本综述描述了该人群中SIRVA的临床特征和结局。此外,还提出了一种建议的诊断算法,以促进SIRVA的早期识别和管理。
151例确诊为SIRVA,其中49.0%在州疫苗接种中心接种疫苗。75.5%怀疑接种部位不当,大多数患者在接种疫苗后24小时内出现肩部疼痛和活动受限,平均持续3个月。
在大流行疫苗接种推广中,提高对SIRVA的认识和教育势在必行。制定一个评估和管理疑似SIRVA的结构化框架将有助于及时诊断和治疗,这对于减轻潜在的长期并发症至关重要。