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这是由于冠状动脉疾病引起的呼吸困难吗?前纵隔原发性神经内分泌肿瘤的罕见病例报告。

Is this dyspnea because of coronary artery disease? A rare case report of primary neuroendocrine tumor in anterior mediastinum.

机构信息

Associate Professor, Cardiologist, Department of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Cardiologist, Department of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.

出版信息

Perfusion. 2024 May;39(4):854-858. doi: 10.1177/02676591231160545. Epub 2023 Mar 9.

Abstract

INTRODUCTION

Mediastinal neuroendocrine tumors are rare malignancies with aggressive behavior and a grim prognosis. These malignancies often go undetected until they are diagnosed at advanced stages.

CASE REPORT

We present the case of 74 -years old man who was hospitalized because of non-ST elevation myocardial infarction and in case of three vessels coronary artery disease, coronary bypass surgery was planned. During preoperative investigation, computer tomography revealed a huge tumor (20 cm × 11 cm × 21 cm in size) in the anterior mediastinum. Successful simultaneous operation coronary bypass surgery and removal of the mediastinal tumor was performed.

DISCUSSION

Surgery is the treatment of choice for neuroendocrine tumors but the relapse rate ranges between 5% and 30% and is higher (65%) in atypical neuroendocrine tumors and patients with mediastinal node involvement. Despite the poor prognosis of neuroendocrine tumors, the spread to the lymph nodes, the patient continues chemotherapy treatment 49 months after the operation.

摘要

简介

纵隔神经内分泌肿瘤是一种罕见的恶性肿瘤,具有侵袭性和不良预后。这些恶性肿瘤通常在晚期才被诊断出来。

病例报告

我们报告了一例 74 岁男性患者,因非 ST 段抬高型心肌梗死住院,且三支血管冠状动脉疾病,计划进行冠状动脉旁路手术。术前检查发现前纵隔有一个巨大的肿瘤(大小为 20cm×11cm×21cm)。成功地进行了同期冠状动脉旁路手术和纵隔肿瘤切除术。

讨论

手术是神经内分泌肿瘤的治疗选择,但复发率在 5%至 30%之间,非典型神经内分泌肿瘤和纵隔淋巴结受累患者的复发率更高(65%)。尽管神经内分泌肿瘤预后不良,但淋巴结转移后,该患者在手术后 49 个月继续接受化疗治疗。

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