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脊髓栓系综合征患者与健康儿童的超声表现比较。

Comparison of Ultrasonographic Findings between Patients with Tethered Cord Syndrome and Healthy Children.

机构信息

Department of Neurosurgery, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Iran J Med Sci. 2023 Mar;48(2):130-136. doi: 10.30476/IJMS.2022.93848.2517.

DOI:10.30476/IJMS.2022.93848.2517
PMID:36895465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9989241/
Abstract

BACKGROUND

Tethered cord syndrome (TCS) is a type of occult spinal dysraphism, which necessitates early detection as an essential component of patient management in reducing complications. This study aimed to compare the findings of spinal cord ultrasonography between TCS patients and healthy individuals.

METHODS

The current study is a case-control study of patients who were admitted to the Akbar and Ghaem Hospitals (Mashhad, Iran) in 2019. The study population comprised 30 children with TCS aged under two years old, and the control group included 34 healthy peers of the same age. The maximum distance of the spinal cord from the posterior canal wall was measured in millimeters using ultrasonography. Demographic and sonographic findings of each participant were recorded in checklists, which were then entered into SPSS software. P values less than 0.05 were considered statistically significant.

RESULTS

The study included 30 children with TCS and 34 healthy individuals with a mean age of 7.67±6.39 months. TCS patients had a significantly shorter maximum distance of the spinal cord from the posterior wall of the spinal canal than the control group (1.75±0.62 mm vs. 2.79±0.76, P<0.001). After performing corrective surgery, the TCS patients indicated significant improvement in this interval (1.57±0.54 mm to 2.95±0.49 mm, respectively, P=0.001).

CONCLUSION

In comparison to children without TCS, the spinal cord was substantially closer to the posterior canal wall in TCS patients. However, these outcomes were improved significantly in patients after surgery.

摘要

背景

脊髓栓系综合征(TCS)是一种隐性脊柱发育不良,作为减少并发症的患者管理的重要组成部分,早期检测至关重要。本研究旨在比较 TCS 患者和健康个体的脊髓超声检查结果。

方法

本研究是 2019 年阿克巴尔和加姆医院(伊朗马什哈德)收治的患者的病例对照研究。研究人群包括 30 名年龄在 2 岁以下的 TCS 患儿,对照组包括 34 名年龄相同的健康同龄人。使用超声测量脊髓距后管壁的最大距离(毫米)。每位参与者的人口统计学和超声检查结果均记录在检查表中,然后输入 SPSS 软件。P 值小于 0.05 被认为具有统计学意义。

结果

本研究包括 30 名 TCS 患儿和 34 名健康个体,平均年龄为 7.67±6.39 个月。TCS 患者脊髓距椎管后壁的最大距离明显短于对照组(1.75±0.62mm 比 2.79±0.76mm,P<0.001)。在进行矫正手术后,TCS 患者的这一间隔显著改善(分别为 1.57±0.54mm 至 2.95±0.49mm,P=0.001)。

结论

与无 TCS 的儿童相比,TCS 患者的脊髓更靠近后管壁。然而,手术后患者的这些结果显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ad/9989241/a119e57401b6/IJMS-48-130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ad/9989241/9c6f42c873c4/IJMS-48-130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ad/9989241/a119e57401b6/IJMS-48-130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ad/9989241/9c6f42c873c4/IJMS-48-130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ad/9989241/a119e57401b6/IJMS-48-130-g002.jpg

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Determination of the normal conus medullaris level in term infants: the role of MRI in early infancy.足月婴儿正常终丝水平的确定:MRI 在婴儿早期的作用。
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Spinal column shortening for secondary tethered cord syndrome: radiographic, clinical, patient-reported, and urodynamic short-term outcomes.
脊柱缩短术治疗继发性脊髓拴系综合征:影像学、临床、患者报告及尿动力学短期结果
J Neurosurg Pediatr. 2021 May 7;28(1):3-12. doi: 10.3171/2020.11.PEDS20847. Print 2021 Jul 1.
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Secondary tethered cord syndrome in adult patients: retethering rates, long-term clinical outcome, and the effect of intraoperative neuromonitoring.成人继发性脊髓栓系综合征:再栓系率、长期临床结局和术中神经监测的影响。
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Retethering : A Neurosurgical Viewpoint.再次拴系:神经外科视角
J Korean Neurosurg Soc. 2020 May;63(3):346-357. doi: 10.3340/jkns.2020.0039. Epub 2020 Apr 27.
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