Obed Aiman, Alsakarneh Saqr, Abuassi Mohammad, Bashir Abdalla, Ahmad Bashar Ali, Jarrad Anwar, Lorf Thomas, Almeqdadi Mohammad
Department of Hepatobiliary and Transplant Surgery, Jordan Hospital, Amman, Jordan.
Department of Internal Medicine, University of Missouri - Kansas City, Kansas City, MO, USA.
Gastroenterology Res. 2023 Feb;16(1):50-55. doi: 10.14740/gr1584. Epub 2023 Feb 28.
Ischemic reperfusion injury (IRI) after liver transplantation is a common cause of early allograft dysfunction with high mortality. The purpose of this case report series is to highlight an unusual clinical course in which complete recovery can occur following the identification of severe hepatic IRI post-transplantation and the implications of this finding on management strategies in patients with IRI post-transplant. Here, we include three cases of severe IRI following liver transplantation that are putatively resolved without retransplantation or definitive therapeutic intervention. All patients recovered until their final follow-up visits to our institution and developed no significant complications from their injury throughout the course of patient care by our institution after discharge from the hospital.
肝移植后的缺血再灌注损伤（IRI）是早期移植物功能障碍的常见原因，死亡率很高。本病例报告系列的目的是突出一种不寻常的临床过程，即移植后发现严重肝IRI后可实现完全康复，以及这一发现对移植后IRI患者管理策略的影响。在此，我们纳入了3例肝移植后严重IRI病例，这些病例在未进行再次移植或明确治疗干预的情况下推测已得到解决。所有患者在最后一次到我们机构随访时均已康复，且在出院后由我们机构进行的整个患者护理过程中，损伤均未引发显著并发症。
